X0306 4 2013-04-29 0 0001069308 Opexa Therapeutics, Inc. OPXA 0001359850 Seaman Scott B C/O OPEXA THERAPEUTICS, INC. 2635 TECHNOLOGY FOREST BLVD. THE WOODLANDS TX 77381 1 0 0 0 Stock Option (Right to Buy) 1.75 2013-04-29 4 A 0 5000 0 A 2023-04-29 Common Stock 5000 5000 D Stock Option (Right to Buy) 1.75 2013-04-29 4 A 0 17143 0 A 2023-04-29 Common Stock 17143 17143 D 50% exercisable on grant date of April 29, 2013 and 50% vested on April 29, 2014. 50% exercisable on grant date of April 29, 2013 and 50% vested on December 31, 2013. /s/ John Ginzler by Power of Attorney 2013-05-01