X0306 4 2013-01-29 0 0001069308 Opexa Therapeutics, Inc. OPXA 0001359850 Seaman Scott B C/O OPEXA THERAPEUTICS, INC. 2635 TECHNOLOGY FOREST BLVD. THE WOODLANDS TX 77381 1 0 0 0 Common Stock Warrant (Right to Buy) 1.21 2013-01-29 4 A 0 22950 A 2013-01-29 2018-01-29 Common Stock 22950 22950 I See Footnote Warrants were issued to all holders of the July 2012 12% Convertible Secured Promissory Notes in exchange for a reduction in the amount of cash collateral held in a controlled account as security for repayment of the Notes. Held by Alkek & Williams Ventures, Ltd. ("Ventures"). Chaswil, Ltd. ("Chaswil") is the investment manager of Ventures and holds voting power and investment power with respect to the Issuer securities held by Ventures. Mr. Seaman is a registered principal of Chaswil and has shared voting power and/or investment power with respect to the Issuer securities held by Ventures. Mr. Seaman disclaims beneficial ownership of the shares held by Ventures except to the extent of any pecuniary interest therein. /s/ John Ginzler, by Power of Attorney 2013-01-31