X0303 4 2010-06-09 0001069308 Opexa Therapeutics, Inc. OPXA 0001313516 JORDEN DAVID EMERSON C/O OPEXA THERAPEUTICS, INC. 2635 N. CRESCENT RIDGE DRIVE THE WOODLANDS TX 77381 1 0 0 0 Common Stock 2010-06-09 4 C 0 159104 .50 A 809104 D Common Stock 2010-06-09 4 C 0 52805 .50 A 861909 D 10% Convertible Promissory Note due 4-14-2011 .50 2010-06-09 4 C 0 79552.00 0 D 2009-04-14 2011-04-14 Common Stock 159104 0 D 10% Convertible Promissory Note due 5-14-2011 .50 2010-06-09 4 C 0 26402.50 0 D 2009-05-14 2011-05-14 Common Stock 52805 0 D The reporting person converted $75,000.00 principal amount of a 10% Convertible Promissory Note due April 14, 2011, and accrued interest thereon of $4,552.00, into shares of common stock at the conversion price of $0.50 pursuant to the terms of the Note. The conversion was an exempt transaction under Rule 16b-6(b). The reporting person converted $25,000.00 principal amount of a 10% Convertible Promissory Note due May 14, 2011, and accrued interest thereon of $1,402.50, into shares of common stock at the conversion price of $0.50 pursuant to the terms of the Note. The conversion was an exempt transaction under Rule 16b-6(b). /s/ David E. Jorden 2010-06-10