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Significant Accounting Policies - Additional Information (Details) - USD ($)
3 Months Ended 12 Months Ended
Jan. 14, 2022
Oct. 12, 2021
Mar. 19, 2021
Jan. 25, 2021
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2021
Dec. 31, 2022
Oct. 04, 2021
Schedule Of Significant Accounting Policies [Line Items]                  
Reimbursement payment     $ 14,000,000.0            
Expected term of stock option granted to employees and directors, average contractual term and vesting period         10 years        
Collaboration agreement amount     25,000,000.0            
Development payments     10,000,000.0            
Deferred collaboration funding, current         $ 2,890,097     $ 8,412,971  
Deferred collaboration funding, non-current         3,661,868        
Cash in excess of FDIC insured limit         6,100,000     2,100,000  
Income tax expense (benefit)         0 $ 0      
Uncertain tax positions, accruals         0 0      
Accruals for interest or penalties related to income tax matters         $ 0 $ 0      
ASU No. 2016-13                  
Schedule Of Significant Accounting Policies [Line Items]                  
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]         true        
Change in Accounting Principle, Accounting Standards Update, Adoption Date         Mar. 31, 2023        
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]         true        
Accounts Payable and Accrued Expenses                  
Schedule Of Significant Accounting Policies [Line Items]                  
Preclinical or clinical study expense         $ 800,000     $ 900,000  
Maximum                  
Schedule Of Significant Accounting Policies [Line Items]                  
Cash, FDIC insured amount         250,000        
Collaboration Agreement | Second Development Payment                  
Schedule Of Significant Accounting Policies [Line Items]                  
Deferred collaboration funding         6,600,000        
Deferred collaboration funding, current         2,900,000        
Deferred collaboration funding, non-current         3,700,000        
Deferred collaboration funding, cash received         $ 35,000,000.0        
Revenue recognized             $ 1,300,000    
Offset to research and development expenses             14,600,000    
Offset to general and administrative expenses             12,600,000    
Collaboration Agreement | Relief                  
Schedule Of Significant Accounting Policies [Line Items]                  
Cash payment received     10,000,000.0       $ 10,000,000.0    
Reimbursement payment     14,000,000.0 $ 14,000,000.0          
Repayment of promissory note of prior loan and interest     $ 4,000,000.0            
Net profit split ratio based on territory     60.00% 60.00%          
Percentage of royalty net sales received     15.00% 15.00%          
Milestone payment to be received     $ 6,000,000.0 $ 6,000,000.0          
Proceeds from development payments subject to acceptance of new drug application                 $ 10,000,000.0
Development and commercialization services and reliefs right of profit percentage     60.00%            
Percentage of payment net profit territory     60.00%            
Upfront non-refundable payment received       $ 1,000,000.0          
Development payments     $ 20,000,000.0            
Collaboration Agreement | Relief | Secured Loan                  
Schedule Of Significant Accounting Policies [Line Items]                  
Debt instrument, term       12 months          
Debt instrument, principal amount       $ 4,000,000.0          
Debt instrument, interest rate       6.00%          
Collaboration Agreement | Relief | Maximum                  
Schedule Of Significant Accounting Policies [Line Items]                  
Development payments     20,000,000.0 $ 20,000,000.0          
Waiver and Agreement | Relief | Second Development Payment                  
Schedule Of Significant Accounting Policies [Line Items]                  
Proceeds from first tranche of development payments subject to new drug application   $ 5,000,000.0              
Proceeds from second tranche of development payments subject to new drug application $ 5,000,000.0                
Collaboration and License Agreement                  
Schedule Of Significant Accounting Policies [Line Items]                  
Upfront non-refundable payment received     $ 1,000,000.0