Stockholders' (Deficit) Equity - Additional Information (Details) - USD ($)								12 Months Ended
	Nov. 29, 2022	Apr. 30, 2020	Mar. 18, 2020	Sep. 18, 2019	Nov. 09, 2018	May 14, 2018	Sep. 19, 2017	Dec. 31, 2022	Dec. 31, 2021	Feb. 18, 2022	Jan. 01, 2022	Jan. 01, 2021
Stockholders Equity [Line Items]
Proceeds from issuance of common stock, net of issuance costs								$ 8,909,718	$ 3,139,047
Number of share outstanding								2,794,850	1,954,975
Awards granted under the plan								960,500
Unrecognized compensation expense								$ 2,200,000
Unrecognized compensation expense remaining vesting period								2 years 7 months 6 days
Weighted average grant date fair value of options granted								$ 1.99	$ 2.57
Fair value of options vested								$ 2,200,000	$ 2,000,000.0
Lincoln Park
Stockholders Equity [Line Items]
Issuance of common stock, net of issuance costs, shares								772,057	200,000
Proceeds from issuance of common stock, net of issuance costs								$ 1,100,000	$ 500,000
Number of shares, company may sell on any single business day		50,000
Maximum amount of Common stock at time of sale, per regular purchase		$ 1,000,000.0
Maximum percentage of shares may be issued or sold based on outstanding shares immediately prior to execution of agreement.		19.99%
Issuance of common stock for commitment fee, shares		148,148
Fair value of the commitment fee shares, recorded to general and administrative expense along with other costs		$ 400,000
2018 Stock Incentive Plan
Stockholders Equity [Line Items]
Number of common stock authorized for issuance						500,000					572,410	529,325
Grant of inducement awards and reserved, shares										200,000
Share-based compensation arrangement by share-based payment award, description								In addition, the number of shares authorized for issuance under the 2018 Plan is automatically increased (the “evergreen provision”) on the first day of each fiscal year beginning on January 1, 2019, and ending on (and including) January 1, 2028, in an amount equal to the lesser of (i) 4% of the outstanding shares of common stock on the last day of the immediately preceding fiscal year, or (ii) another amount (including zero) determined by the Company’s Board of Directors. On January 1, 2022 and 2021, 572,410 and 529,325 additional shares, respectively, were authorized according to the evergreen provision. On February 18, 2022, the Company’s Board of Directors amended and restated the 2018 Plan to add a provision permitting the grant of inducement awards under Nasdaq Marketplace Rule 5635(c)(4) to eligible recipients and initially reserved 200,000 shares of the Company’s common stock for issuance pursuant to inducement awards granted under the 2018 Plan. Any shares subject to awards granted under the 2018 Plan that are forfeited or terminated before being exercised or settled, or are not delivered to the participant because such award is settled in cash, will again become available for issuance under the 2018 Plan. Shares withheld to satisfy the grant, exercise price or tax withholding obligation related to an award will again become available for issuance under the 2018 Plan.
Share-based compensation arrangement by share-based payment award, expiration date								Jan. 01, 2028
Share-based compensation arrangement by share-based payment award, percentage of outstanding our common stock								4.00%
Available for the grant of future awards								389,313
Options contractual term						10 years
2013 Stock Incentive Plan
Stockholders Equity [Line Items]
Number of common stock authorized for issuance							165,000
Options contractual term							10 years
Awards granted under the plan								0
2010 Stock Incentive Plan
Stockholders Equity [Line Items]
Number of common stock authorized for issuance							470,170
Options contractual term							10 years
Awards granted under the plan								0
Executive Officers and Employees | 2018 Stock Incentive Plan
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, stock options vesting period						4 years
Executive Officers and Employees | 2018 Stock Incentive Plan | One-year Anniversary of the Grant Date
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, Vesting percentage Share-based compensation arrangement by share-based payment award, Vesting percentage						25.00%
Executive Officers and Employees | 2018 Stock Incentive Plan | One-year Anniversary of the Grant Date | Restricted Stock Units
Stockholders Equity [Line Items]
Awards granted under the plan								0	0
Executive Officers and Employees | 2018 Stock Incentive Plan | One-year Anniversary of the Grant Date | Unvested Restricted Stock Units
Stockholders Equity [Line Items]
Awards granted under the plan								0	0
Executive Officers and Employees | 2018 Stock Incentive Plan | Quarterly over Remaining Three Years
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, Vesting percentage Share-based compensation arrangement by share-based payment award, Vesting percentage						75.00%
Executive Officers and Employees | 2018 Stock Incentive Plan | January 1, 2021
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, Vesting percentage Share-based compensation arrangement by share-based payment award, Vesting percentage				50.00%
Executive Officers and Employees | 2018 Stock Incentive Plan | January 1, 2022
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, Vesting percentage Share-based compensation arrangement by share-based payment award, Vesting percentage				50.00%
Board of Directors | 2018 Stock Incentive Plan
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, stock options vesting period						12 months
Weighted Average | Lincoln Park
Stockholders Equity [Line Items]
Issuance of common stock, price per share								$ 1.42	$ 2.47
Maximum | Lincoln Park
Stockholders Equity [Line Items]
Shares value might be issued under agreement		$ 15,000,000.0
Number of shares, company may sell on any single business day		100,000
Beneficially ownership percentage		9.99%
Maximum | 2010 and 2013 Stock Incentive Plan
Stockholders Equity [Line Items]
Number of share outstanding						635,170
Minimum | Lincoln Park
Stockholders Equity [Line Items]
Threshold price per share for issuance of shares under agreement		$ 2.1668
At-the-Market Facility
Stockholders Equity [Line Items]
Issuance of common stock, net of issuance costs, shares								3,312,471	877,107
Proceeds from issuance of common stock gross								$ 6,500,000	$ 2,800,000
Common stock offering costs								200,000	200,000
Proceeds from issuance of common stock, net of issuance costs								6,300,000	$ 2,600,000
Amount remained available under facility								$ 33,500,000
At-the-Market Facility | Weighted Average
Stockholders Equity [Line Items]
Issuance of common stock, gross sale price per share								$ 1.9749	$ 3.1692
At-the-Market Facility | Maximum
Stockholders Equity [Line Items]
Aggregate offering price of common stock			$ 50,000,000.0		$ 50,000,000.0
Private Placement | President and Chief Executive Officer and Member and Chairman of Board of Directors
Stockholders Equity [Line Items]
Issuance of common stock, net of issuance costs, shares	1,229,508
Issuance of common stock, price per share	$ 1.22
Proceeds from issuance of common stock, net of issuance costs	$ 1,500,000