<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2006-04-13</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001069308</issuerCik>
        <issuerName>PharmaFrontiers Corp.</issuerName>
        <issuerTradingSymbol>PFTR.OB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001010207</rptOwnerCik>
            <rptOwnerName>ROTH MICHAEL</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O SF CAPITAL PARTNERS LTD.</rptOwnerStreet1>
            <rptOwnerStreet2>3600 SOUTH LAKE DRIVE</rptOwnerStreet2>
            <rptOwnerCity>ST. FRANCIS</rptOwnerCity>
            <rptOwnerState>WI</rptOwnerState>
            <rptOwnerZipCode>53235</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001010208</rptOwnerCik>
            <rptOwnerName>STARK BRIAN JAY</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O SF CAPITAL PARTNERS LTD.</rptOwnerStreet1>
            <rptOwnerStreet2>3600 SOUTH LAKE DRIVE</rptOwnerStreet2>
            <rptOwnerCity>ST. FRANCIS</rptOwnerCity>
            <rptOwnerState>WI</rptOwnerState>
            <rptOwnerZipCode>53235</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, par value $0.05 per share</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10000000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                    <footnoteId id="F1"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By SF Capital Partners Ltd.</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Common Stock Purchase Warrant</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.65</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2011-04-13</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>5000000</value>
                    <footnoteId id="F3"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                    <footnoteId id="F1"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By SF Capital Partners Ltd.</value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Represents the combined indirect holdings of Michael A. Roth and Brian J. Stark (the &quot;Reporting Persons&quot;).  All of the
 foregoing represents securities held directly by SF Capital Partners Ltd. (&quot;SF Capital&quot;).   The Reporting Persons are the
 Managing Members of Stark Offshore Management, LLC (&quot;Stark Offshore&quot;), which acts as investment manager and has sole power
 to direct the management of SF Capital.  Through Stark Offshore, the Reporting Persons possess voting and dispositive power
 over all of the foregoing shares.  Therefore, for the purposes of Rule 13d-3 under the Securities Exchange Act of 1934, as
 amended, the Reporting Persons may be deemed to be the beneficial owners of, but hereby disclaim such beneficial ownership
 of, the foregoing shares.</footnote>
        <footnote id="F2">Immed.</footnote>
        <footnote id="F3">Such warrants are subject to conversion caps that preclude the holder thereof from utilizing its exercise rights to the
 extent that it would beneficially own in excess of 9.999% of the Common Stock of the Issuer, giving effect to such exercise.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Michael Roth</signatureName>
        <signatureDate>2006-04-17</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Todd M.W. Turall, as Attorney-in-fact for Brian J. Stark</signatureName>
        <signatureDate>2006-04-17</signatureDate>
    </ownerSignature>
</ownershipDocument>
