Cash, Cash Equivalents and Investments (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	$ 1,161,037	$ 1,183,222
Gross Unrealized Gains	107	57
Gross Unrealized Losses	(36,675)	(52,379)
Fair Value	1,124,469	1,130,900
Cash and Cash Equivalents	263,414	353,684
Marketable Securities	54,810	39,240
Short-Term Investments	775,129	581,769
Long-Term Investments	31,116	156,207
Debt securities, available-for-sale, unrealized Loss	375,600
Continuous unrealized loss position of available-for-sale investments, unrealized losses	17,600
Continuous unrealized loss position of available-for-sale investments, gross unrealized losses	600
Share Purchase Agreement with CLBT
Restricted Cash and Cash Equivalents Items [Line Items]
Marketable securities, unrealized gain (loss)	15,600
Common stock | Share Purchase Agreement with CLBT
Restricted Cash and Cash Equivalents Items [Line Items]
Marketable Securities			$ 90,000
Investment owned, shares held			9,000,000
Fair Value, Inputs, Level 1
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	341,662	378,805
Gross Unrealized Gains	45	24
Gross Unrealized Losses	(35,422)	(51,026)
Fair Value	306,285	327,803
Cash and Cash Equivalents	49,968	115,769
Marketable Securities	54,810	39,240
Short-Term Investments	195,771	78,427
Long-Term Investments	5,736	94,367
Fair Value, Inputs, Level 2
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	605,929	660,673
Gross Unrealized Gains	62	33
Gross Unrealized Losses	(1,253)	(1,353)
Fair Value	604,738	659,353
Cash and Cash Equivalents		94,171
Short-Term Investments	579,358	503,342
Long-Term Investments	25,380	61,840
Cash
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	213,446	143,744
Fair Value	213,446	143,744
Cash and Cash Equivalents	213,446	143,744
Money market funds | Fair Value, Inputs, Level 1
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	49,968	2,669
Fair Value	49,968	2,669
Cash and Cash Equivalents	49,968	2,669
Agency bonds | Fair Value, Inputs, Level 1
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	160,615	164,486
Gross Unrealized Gains	39	6
Gross Unrealized Losses	(230)	(263)
Fair Value	160,424	164,229
Short-Term Investments	154,688	69,862
Long-Term Investments	5,736	94,367
Treasury bills | Fair Value, Inputs, Level 1
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	41,079
Gross Unrealized Gains	6
Gross Unrealized Losses	(2)
Fair Value	41,083
Short-Term Investments	41,083
Marketable securities | Fair Value, Inputs, Level 1
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	90,000	90,000
Gross Unrealized Losses	(35,190)	(50,760)
Fair Value	54,810	39,240
Marketable Securities	54,810	39,240
State and municipal obligations | Fair Value, Inputs, Level 2
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	3,026	4,980
Gross Unrealized Losses	(14)	(33)
Fair Value	3,012	4,947
Short-Term Investments	3,012	4,947
Corporate bonds | Fair Value, Inputs, Level 2
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost		257,422
Gross Unrealized Gains		33
Gross Unrealized Losses		(1,159)
Fair Value		256,296
Cash and Cash Equivalents		28,883
Short-Term Investments		168,074
Long-Term Investments		59,339
Treasury bills | Fair Value, Inputs, Level 1
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost		121,650
Gross Unrealized Gains		18
Gross Unrealized Losses		(3)
Fair Value		121,665
Cash and Cash Equivalents		113,100
Short-Term Investments		8,565
Certificates of deposit | Fair Value, Inputs, Level 2
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost		5,002
Fair Value		5,002
Short-Term Investments		5,002
Term deposits | Fair Value, Inputs, Level 2
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	175,000	200,000
Fair Value	175,000	200,000
Cash and Cash Equivalents		25,000
Short-Term Investments	175,000	175,000
Corporate bonds | Fair Value, Inputs, Level 2
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	241,401
Gross Unrealized Gains	45
Gross Unrealized Losses	(1,081)
Fair Value	240,365
Short-Term Investments	226,468
Long-Term Investments	13,897
Commercial paper | Fair Value, Inputs, Level 2
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	140,029	160,241
Fair Value	140,029	160,241
Cash and Cash Equivalents		40,288
Short-Term Investments	140,029	119,953
U.S. government | Fair Value, Inputs, Level 2
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	43,948	30,525
Gross Unrealized Losses	(158)	(159)
Fair Value	43,790	30,366
Short-Term Investments	32,307	30,366
Long-Term Investments	11,483
Treasury inflation-protected securities | Fair Value, Inputs, Level 2
Restricted Cash and Cash Equivalents Items [Line Items]
Amortized Cost	2,525	2,503
Gross Unrealized Gains	17
Gross Unrealized Losses		(2)
Fair Value	2,542	2,501
Short-Term Investments	$ 2,542
Long-Term Investments		$ 2,501