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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 Pgm2McjioAxx6Hz7cVJuCFfNNRGls6UTJgNtdYUa1BFA+W2a0rKsoFkbZnuaM5vR
 aBPVkn9/VpkBq643+iZBQw==

<SEC-DOCUMENT>0000919574-10-002287.txt : 20100311
<SEC-HEADER>0000919574-10-002287.hdr.sgml : 20100311
<ACCEPTANCE-DATETIME>20100311165237
ACCESSION NUMBER:		0000919574-10-002287
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100310
FILED AS OF DATE:		20100311
DATE AS OF CHANGE:		20100311

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			ZACKS ANDREW
		CENTRAL INDEX KEY:			0001437688

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-28401
		FILM NUMBER:		10674584

	MAIL ADDRESS:	
		STREET 1:		C/O CONUS PARTNERS, INC.
		STREET 2:		49 WEST 38TH STREET, 11TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MAXYGEN INC
		CENTRAL INDEX KEY:			0001068796
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				770449487
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		515 GALVESTON DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063
		BUSINESS PHONE:		6502985300

	MAIL ADDRESS:	
		STREET 1:		515 GALVESTON DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CONUS PARTNERS INC
		CENTRAL INDEX KEY:			0001174784

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-28401
		FILM NUMBER:		10674585

	BUSINESS ADDRESS:	
		STREET 1:		49 WEST 38TH STREET
		STREET 2:		11TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018
		BUSINESS PHONE:		212-332-7265

	MAIL ADDRESS:	
		STREET 1:		49 WEST 38TH STREET
		STREET 2:		11TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>p1080212.xml
<DESCRIPTION>CONUS/MAXYGEN
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-03-10</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001068796</issuerCik>
        <issuerName>MAXYGEN INC</issuerName>
        <issuerTradingSymbol>MAXY</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001174784</rptOwnerCik>
            <rptOwnerName>CONUS PARTNERS INC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>49 WEST 38TH STREET</rptOwnerStreet1>
            <rptOwnerStreet2>11TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10018</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001437688</rptOwnerCik>
            <rptOwnerName>ZACKS ANDREW</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O CONUS PARTNERS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>49 WEST 38TH STREET, 11TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10018</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2010-03-10</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness></transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>60000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>5.95</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3135950</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">These shares of Common Stock (the &quot;Shares&quot;) of Maxygen, Inc. (the &quot;Issuer&quot;) are held in the accounts of private investment vehicles and certain managed accounts
over which Conus Partners, Inc. and Andrew Zacks (the &quot;Reporting Persons&quot;) each has investment discretion.  Conus Partners, Inc. has investment discretion over
the Shares because it is the investment adviser to such private investment vehicles and managed accounts.  Andrew Zacks has investment discretion over the Shares
because he is the managing director of Conus Partners, Inc.</footnote>
    </footnotes>

    <remarks>+ The Reporting Persons hereby disclaim beneficial ownership over the securities reported on this Form 4 except to the extent of their pecuniary interest therein.  This report shall not be deemed an admission that the Reporting Persons are the beneficial owners of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.</remarks>

    <ownerSignature>
        <signatureName>Conus Partners, Inc.(+), By: /s/ Andrew Zacks, as Managing Director</signatureName>
        <signatureDate>2010-03-11</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Andrew Zacks(+)</signatureName>
        <signatureDate>2010-03-11</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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