X0306 4 2019-05-09 0 0001103021 BIODELIVERY SCIENCES INTERNATIONAL INC BDSI 0001066040 ODONNELL FRANCIS E JR C/O BIODELIVERY SCIENCES INTL, INC., 4131 PARKLAKE AVE. SUITE 225 RALEIGH NC 27612 1 0 0 0 Common Stock 2019-05-09 4 M 0 22500 A 620754 D Restricted Stock Units 2019-05-09 4 M 0 22500 0.00 D 2020-05-09 Common Stock 22500 22500 D The shares of common stock were acquired by the Reporting Person as a result of the vesting of 22,500 of Restricted Stock Units ("RSUs") granted to the Reporting Person on April 17, 2019 under the Issuer's 2011 Equity Incentive Plan, as amended . The remainder of the RSUs under this grant will vest in the first open window upon the filing of the Company's Quarterly Report for March 31, 2020. /s/ Francis E. O'Donnell Jr. 2019-05-10