X0306 4 2019-01-31 0 0001103021 BIODELIVERY SCIENCES INTERNATIONAL INC BDSI 0001066040 ODONNELL FRANCIS E JR C/O BIODELIVERY SCIENCES INTL, INC., 4131 PARKLAKE AVENUE, SUITE 225 RALEIGH NC 27612 1 0 0 0 Common Stock 2019-02-01 4 S 0 8000 4.60 D 498187 D The shares of Common Stock were automatically sold under a pre-planned 10b5-1 trading plan. The Reporting Person undertakes to provide the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes. On February 1, 2019, the Reporting Person sold an aggregate of 8,000 shares of the Issuer's Common Stock at a weighted average price of $4.60 per share. The highest sale price for the Common Stock was $4.68 per share and the lowest sale price was $4.52 per share. /s/ Francis E. O'Donnell Jr. 2019-02-04