NPORT-P false 0001064642 XXXXXXXX S000010018 C000027706 SPDR SERIES TRUST 811-08839 0001064642 5493004JVD6CQEEJSS37 One Congress Street Boston 02114 1-866-787-2257 State Street(R) SPDR(R) S&P(R) Biotech ETF S000010018 549300Y3ODFMPD5XXL58 2026-06-30 2026-03-31 N 8032185318.08 597736408.77 7434448909.31 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 ACMBS UST ADMA Biologics Inc N/A 000899104 4916092.00000000 NS USD 44293988.92000000 0.595793843771 Long EC CORP US N 1 N N Absci Corp N/A 00091E109 4448453.00000000 NS USD 13345359.00000000 0.179507037613 Long EC CORP US N 1 N N AbbVie Inc FR5LCKFTG8054YNNRU85 00287Y109 372103.00000000 NS USD 80928681.47000000 1.088563287705 Long EC CORP US N 1 N N N ACADIA Pharmaceuticals Inc 529900O3044NO0PEA039 004225108 3412655.00000000 NS USD 75965700.30000000 1.021806743535 Long EC CORP US N 1 N N N Invivyd Inc N/A 00534A102 5654625.00000000 NS USD 7351012.50000000 0.098877705525 Long EC CORP US N 1 N N Spyre Therapeutics Inc 52990017AIJPRH3HQH40 00773J202 1069556.00000000 NS USD 53948404.64000000 0.725654386735 Long EC CORP US N 1 N N Agios Pharmaceuticals Inc 529900ONJHY8EOGYT555 00847X104 1930324.00000000 NS USD 65302860.92000000 0.878381998674 Long EC CORP US N 1 N N Akebia Therapeutics Inc 549300CBQEHMKEEGNX42 00972D105 6038997.00000000 NS USD 8394205.83000000 0.112909590642 Long EC CORP US N 1 N N CONTRA AKERO THERAPEUT 549300SI3KG74LBE2955 009CVR044 2033975.00000000 NS USD 1322083.75000000 0.017783211185 N/A DE US N 2 N/A N/A Akero Therapeutics, Inc. Akero Therapeutics, Inc. 2099-12-31 XXXX 0.00000000 N N N Allogene Therapeutics Inc N/A 019770106 5212606.00000000 NS USD 12718758.64000000 0.171078701261 Long EC CORP US N 1 N N State Street Global Advisors 5493008BJIBKQ5KTIF74 857492706 595460501.00000000 NS USD 595460501.00000000 8.009477343429 Long STIV RF US N 1 N N Alnylam Pharmaceuticals Inc 529900S3ZI14OWRJII50 02043Q107 264406.00000000 NS USD 87484013.22000000 1.176738374117 Long EC CORP US N 1 N N N Altimmune Inc 549300EOYCQ8SW3NVE64 02155H200 4353091.00000000 NS USD 13407520.28000000 0.180343162533 Long EC CORP US N 1 N N Amgen Inc 62QBXGPJ34PQ72Z12S66 031162100 224546.00000000 NS USD 79006510.10000000 1.062708360280 Long EC CORP US N 1 N N N Amicus Therapeutics Inc 549300MRD1SMUTNBPQ53 03152W109 5895670.00000000 NS USD 85251388.20000000 1.146707566894 Long EC CORP US N 1 N N N AnaptysBio Inc 529900HH4WQT03IG1A12 032724106 512175.00000000 NS USD 28405225.50000000 0.382075737509 Long EC CORP US N 1 N N N Anavex Life Sciences Corp 549300K1I5L8COCQ8W36 032797300 2653883.00000000 NS USD 8147420.81000000 0.109590110973 Long EC CORP US N 1 N N Annexon Inc N/A 03589W102 3823368.00000000 NS USD 21181458.72000000 0.284909600945 Long EC CORP US N 1 N N Apellis Pharmaceuticals Inc 254900HS0ZFRXXSB9D42 03753U106 3390454.00000000 NS USD 136397964.42000000 1.834674850602 Long EC CORP US N 1 N N Apogee Therapeutics Inc N/A 03770N101 1134394.00000000 NS USD 95481942.98000000 1.284317696506 Long EC CORP US N 1 N N Arbutus Biopharma Corp 25490064CESONAUIAS23 03879J100 2268065.00000000 NS USD 10206292.50000000 0.137283780203 Long EC CORP CA N 1 N N Arcellx Inc N/A 03940C100 740785.00000000 NS USD 85056933.70000000 1.144091979615 Long EC CORP US N 1 N N N Ardelyx Inc 549300F542QR4SXHCY32 039697107 7664448.00000000 NS USD 45910043.52000000 0.617531226322 Long EC CORP US N 1 N N Arcus Biosciences Inc N/A 03969F109 2163363.00000000 NS USD 46728640.80000000 0.628542093301 Long EC CORP US N 1 N N N Arcutis Biotherapeutics Inc N/A 03969K108 3437805.00000000 NS USD 80994685.80000000 1.089451105092 Long EC CORP US N 1 N N N ArriVent Biopharma Inc N/A 04272N102 701088.00000000 NS USD 16174100.16000000 0.217556141111 Long EC CORP US N 1 N N Arrowhead Pharmaceuticals Inc 549300O3CSB8T7OZ3D66 04280A100 1458207.00000000 NS USD 91429578.90000000 1.229809768219 Long EC CORP US N 1 N N Bicara Therapeutics Inc N/A 055477103 701643.00000000 NS USD 13955679.27000000 0.187716392166 Long EC CORP US N 1 N N Beam Therapeutics Inc N/A 07373V105 3248626.00000000 NS USD 77414757.58000000 1.041297862482 Long EC CORP US N 1 N N BioCryst Pharmaceuticals Inc 549300Z0INP1Z5NP6J59 09058V103 6655054.00000000 NS USD 63356114.08000000 0.852196509154 Long EC CORP US N 1 N N N BioMarin Pharmaceutical Inc NSLL8ITTRR0J5HEMR848 09061G101 1404601.00000000 NS USD 79345910.49000000 1.067273599669 Long EC CORP US N 1 N N N Biogen Inc W8J5WZB5IY3K0NDQT671 09062X103 444855.00000000 NS USD 81555267.15000000 1.096991426598 Long EC CORP US N 1 N N N CONTRA BLUEPRINT MEDIC 5299004CC60O9T5HVM83 096CVR048 756469.00000000 NS USD 347975.74000000 0.004680585531 N/A DE US N 2 N/A N/A Blueprint Medicines Corp. Blueprint Medicines Corp. 2099-12-31 XXXX 0.00000000 N N N Bridgebio Pharma Inc 54930028YG89VTY2J114 10806X102 1186816.00000000 NS USD 88132956.16000000 1.185467238192 Long EC CORP US N 1 N N Capricor Therapeutics Inc 5493002ZI5PDLXV4DX14 14070B309 1171894.00000000 NS USD 35625577.60000000 0.479195943567 Long EC CORP US N 1 N N CareDx Inc 549300NQOFKL9NON0U06 14167L103 1480419.00000000 NS USD 25700073.84000000 0.345689023537 Long EC CORP US N 1 N N N Catalyst Pharmaceuticals Inc 5299004O0R5XXLA5H544 14888U101 2268292.00000000 NS USD 56162909.92000000 0.755441467217 Long EC CORP US N 1 N N Celcuity Inc 25490070W7UU7W2SEY87 15102K100 731925.00000000 NS USD 83541919.50000000 1.123713680988 Long EC CORP US N 1 N N Celldex Therapeutics Inc 529900F018DMYWH38923 15117B202 1222480.00000000 NS USD 38777065.60000000 0.521586281283 Long EC CORP US N 1 N N CG oncology Inc N/A 156944100 1276920.00000000 NS USD 86421945.60000000 1.162452612886 Long EC CORP US N 1 N N Cogent Biosciences Inc N/A 19240Q201 2348101.00000000 NS USD 90378407.49000000 1.215670570777 Long EC CORP US N 1 N N N Compass Therapeutics Inc N/A 20454B104 3684989.00000000 NS USD 19493591.81000000 0.262206278471 Long EC CORP US N 1 N N Corvus Pharmaceuticals Inc 549300I3AVJ8F75NCX65 221015100 2116858.00000000 NS USD 30969632.54000000 0.416569310217 Long EC CORP US N 1 N N Cullinan Therapeutics Inc N/A 230031106 1307461.00000000 NS USD 18579020.81000000 0.249904478955 Long EC CORP US N 1 N N Cytokinetics Inc 549300BE5DY1HW7IHA64 23282W605 1331453.00000000 NS USD 87756067.23000000 1.180397744345 Long EC CORP US N 1 N N CytomX Therapeutics Inc 5493004VW2FW0QLL3345 23284F105 4511036.00000000 NS USD 21201869.20000000 0.285184140191 Long EC CORP US N 1 N N Day One Biopharmaceuticals Inc N/A 23954D109 1113401.00000000 NS USD 23871317.44000000 0.321090611169 Long EC CORP US N 1 N N N Denali Therapeutics Inc 549300ZTQ2HO18L3Q830 24823R105 2830854.00000000 NS USD 54352396.80000000 0.731088443313 Long EC CORP US N 1 N N Dianthus Therapeutics Inc 549300Z3N6ODPCOFC890 252828108 586673.00000000 NS USD 49233598.16000000 0.662236014539 Long EC CORP US N 1 N N Disc Medicine Inc N/A 254604101 1012048.00000000 NS USD 64710349.12000000 0.870412184001 Long EC CORP US N 1 N N Dyne Therapeutics Inc N/A 26818M108 3437524.00000000 NS USD 62322310.12000000 0.838290919478 Long EC CORP US N 1 N N Emergent BioSolutions Inc 549300YW6TUOX8BE5103 29089Q105 1572925.00000000 NS USD 13055277.50000000 0.175605181490 Long EC CORP US N 1 N N Erasca Inc N/A 29479A108 4733094.00000000 NS USD 76581460.92000000 1.030089275670 Long EC CORP US N 1 N N N Exelixis Inc 254900PJQB59O2O95R37 30161Q104 2029215.00000000 NS USD 87033031.35000000 1.170672263831 Long EC CORP US N 1 N N N 4D Molecular Therapeutics Inc N/A 35104E100 1318068.00000000 NS USD 12271213.08000000 0.165058812424 Long EC CORP US N 1 N N Damora Therapeutics Inc N/A 36322Q206 93797.00000000 NS USD 2429342.30000000 0.032676830920 Long EC CORP US N 1 N N N Geron Corp 549300T282D7Z2YESL90 374163103 16613693.00000000 NS USD 24754402.57000000 0.332968897519 Long EC CORP US N 1 N N Gilead Sciences Inc 549300WTZWR07K8MNV44 375558103 580264.00000000 NS USD 80871393.68000000 1.087792715593 Long EC CORP US N 1 N N N GRAIL Inc 2549009XSNESW3VE8024 384747101 1041295.00000000 NS USD 53814125.60000000 0.723848213316 Long EC CORP US N 1 N N Halozyme Therapeutics Inc 529900242I3SV9AGM753 40637H109 1274489.00000000 NS USD 82370224.07000000 1.107953327473 Long EC CORP US N 1 N N Hyperliquid Strategies Inc 98450073FF7E1B63N260 44916Y106 2451336.00000000 NS USD 12477300.24000000 0.167830869405 Long EC CORP US N 1 N N Ideaya Biosciences Inc 549300ULW08F62IJML11 45166A102 1628726.00000000 NS USD 54269150.32000000 0.729968703558 Long EC CORP US N 1 N N ImmunityBio Inc 529900J9XLBR4HFL4B83 45256X103 10244025.00000000 NS USD 78571671.75000000 1.056859394804 Long EC CORP US N 1 N N Immunome Inc N/A 45257U108 2934802.00000000 NS USD 64184119.74000000 0.863333927275 Long EC CORP US N 1 N N Immunovant Inc N/A 45258J102 2566528.00000000 NS USD 63752555.52000000 0.857529001782 Long EC CORP US N 1 N N Incyte Corp 549300Z4WN6JVZ3T4680 45337C102 895013.00000000 NS USD 84238623.56000000 1.133084974926 Long EC CORP US N 1 N N N Inhibrx Biosciences Inc N/A 45720N103 296581.00000000 NS USD 19939140.63000000 0.268199309366 Long EC CORP US N 1 N N Insmed Inc 529900Q55QAG41CCAC11 457669307 607845.00000000 NS USD 99394814.40000000 1.336949323513 Long EC CORP US N 1 N N N CONTRA INHIBRX INC 549300VBKG2LTV1TLY22 457CVR017 1645973.00000000 NS USD 1069882.45000000 0.014390877697 N/A DE US N 2 N/A N/A Inhibrx, Inc. Inhibrx, Inc. 2099-12-31 XXXX 0.00000000 N N Intellia Therapeutics Inc 5493002T5BCPE5DZC723 45826J105 3753333.00000000 NS USD 48117729.06000000 0.647226575190 Long EC CORP US N 1 N N Ionis Pharmaceuticals Inc 549300SI4ZGLG0BLUZ92 462222100 1132906.00000000 NS USD 85069911.54000000 1.144266543192 Long EC CORP US N 1 N N Iovance Biotherapeutics Inc 2549002L8WT2ACU5Q878 462260100 8139873.00000000 NS USD 28570954.23000000 0.384304937440 Long EC CORP US N 1 N N Ironwood Pharmaceuticals Inc 549300PC8MR6QHH6P296 46333X108 3999224.00000000 NS USD 14037276.24000000 0.188813944533 Long EC CORP US N 1 N N Perspective Therapeutics Inc 5493005LRKM6BCABC605 46489V302 1713495.00000000 NS USD 7145274.15000000 0.096110340351 Long EC CORP US N 1 N N Janux Therapeutics Inc N/A 47103J105 1424540.00000000 NS USD 19801106.00000000 0.266342619897 Long EC CORP US N 1 N N N KalVista Pharmaceuticals Inc 529900Q7IDA3WUGRZA51 483497103 1077952.00000000 NS USD 21699173.76000000 0.291873332168 Long EC CORP US N 1 N N Kodiak Sciences Inc 254900IXI5NI8C9OQE24 50015M109 1344151.00000000 NS USD 51239036.12000000 0.689210952217 Long EC CORP US N 1 N N Krystal Biotech Inc 549300YONUY68210OE41 501147102 332277.00000000 NS USD 85833794.64000000 1.154541455419 Long EC CORP US N 1 N N Kura Oncology Inc 5493005QORQTZCZYOP39 50127T109 2523230.00000000 NS USD 20513859.90000000 0.275929798566 Long EC CORP US N 1 N N N Kymera Therapeutics Inc N/A 501575104 1039280.00000000 NS USD 86561631.20000000 1.164331509381 Long EC CORP US N 1 N N Lexeo Therapeutics Inc N/A 52886X107 1862707.00000000 NS USD 10691938.18000000 0.143816149797 Long EC CORP US N 1 N N Madrigal Pharmaceuticals Inc 549300CHIMT2EUSNJB60 558868105 196408.00000000 NS USD 102813695.76000000 1.382936341539 Long EC CORP US N 1 N N MannKind Corp 213800GFBCNY1ZFST722 56400P706 10933657.00000000 NS USD 26787459.65000000 0.360315337112 Long EC CORP US N 1 N N CONTRA METSERA INC N/A 592CVR013 1530714.00000000 NS USD 7500498.60000000 0.100888427528 N/A DE US N 2 N/A N/A Metsera, Inc. Metsera, Inc. 2099-12-31 XXXX 0.00000000 N N N MiMedx Group Inc N/A 602496101 2282660.00000000 NS USD 9016507.00000000 0.121280099036 Long EC CORP US N 1 N N Mineralys Therapeutics Inc N/A 603170101 1773248.00000000 NS USD 48037288.32000000 0.646144575152 Long EC CORP US N 1 N N Mirum Pharmaceuticals Inc 254900YZKR40F7F27K81 604749101 923473.00000000 NS USD 85310435.74000000 1.147501809221 Long EC CORP US N 1 N N CONTRA MIRATI THERAPEU 529900GYRW59IDQV6N54 604CVR027 1369552.00000000 NS USD 958686.40000000 0.012895191179 N/A DE US N 2 N/A N/A Mirati Therapeutics, Inc. Mirati Therapeutics, Inc. 2099-12-31 XXXX 0.00000000 N N Moderna Inc 549300EI6OKH5K5Q2G38 60770K107 1513720.00000000 NS USD 76896976.00000000 1.034333236236 Long EC CORP US N 1 N N Monte Rosa Therapeutics Inc N/A 61225M102 1966731.00000000 NS USD 32352724.95000000 0.435173142551 Long EC CORP US N 1 N N Myriad Genetics Inc 52990044IHUOUMETT163 62855J104 2160321.00000000 NS USD 9721444.50000000 0.130762140120 Long EC CORP US N 1 N N Natera Inc 529900CQ3OZ0A0VYVU59 632307104 430933.00000000 NS USD 86182290.67000000 1.159229039318 Long EC CORP US N 1 N N N Neurocrine Biosciences Inc 549300FECER0XBN49756 64125C109 654044.00000000 NS USD 86163756.56000000 1.158979738929 Long EC CORP US N 1 N N N Novavax Inc 529900J4GJHPEPQ23205 670002401 4667715.00000000 NS USD 37995200.10000000 0.511069489662 Long EC CORP US N 1 N N Nuvalent Inc N/A 670703107 846768.00000000 NS USD 86751381.60000000 1.166883822301 Long EC CORP US N 1 N N Nurix Therapeutics Inc N/A 67080M103 2809877.00000000 NS USD 43553093.50000000 0.585828136440 Long EC CORP US N 1 N N Ocugen Inc 549300JVNUI9CXWJLR09 67577C105 5222819.00000000 NS USD 9453302.39000000 0.127155388453 Long EC CORP US N 1 N N Olema Pharmaceuticals Inc N/A 68062P106 2471879.00000000 NS USD 36855715.89000000 0.495742405921 Long EC CORP US N 1 N N OMNIAB INC N/A 68218J202 161959.00000000 NS USD 0.00000000 0.000000 Long EC CORP US N 3 N N OMNIAB INC N/A 68218J301 161959.00000000 NS USD 0.00000000 0.000000 Long EC CORP US N 3 N N ORIC Pharmaceuticals Inc 54930033FJRNEYBW0L25 68622P109 2171512.00000000 NS USD 27513057.04000000 0.370075272230 Long EC CORP US N 1 N N Oruka Therapeutics Inc 529900TG7O4ESUDMGI54 687604108 761033.00000000 NS USD 37328668.65000000 0.502104044366 Long EC CORP US N 1 N N PTC Therapeutics Inc 549300UJLWOIWFDGB318 69366J200 1290071.00000000 NS USD 87892537.23000000 1.182233388139 Long EC CORP US N 1 N N N Palvella Therapeutics Inc 254900AJDH8PAOOI5T33 697947109 274232.00000000 NS USD 34183018.80000000 0.459792234999 Long EC CORP US N 1 N N Praxis Precision Medicines Inc N/A 74006W207 285252.00000000 NS USD 91905341.88000000 1.236209206642 Long EC CORP US N 1 N N Precigen Inc 549300XCWNQU35K64G19 74017N105 6004794.00000000 NS USD 23238552.78000000 0.312579359458 Long EC CORP US N 1 N N Prime Medicine Inc N/A 74168J101 3979993.00000000 NS USD 13850375.64000000 0.186299963977 Long EC CORP US N 1 N N Protagonist Therapeutics Inc N/A 74366E102 878071.00000000 NS USD 92548683.40000000 1.244862726598 Long EC CORP US N 1 N N Recursion Pharmaceuticals Inc N/A 75629V104 16732511.00000000 NS USD 51368808.77000000 0.690956510652 Long EC CORP US N 1 N N Regeneron Pharmaceuticals Inc 549300RCBFWIRX3HYQ56 75886F107 109400.00000000 NS USD 84526816.00000000 1.136961421500 Long EC CORP US N 1 N N N REGENXBIO Inc 549300EOES47LATSET33 75901B107 1363810.00000000 NS USD 11428727.80000000 0.153726630439 Long EC CORP US N 1 N N Relay Therapeutics Inc N/A 75943R102 2831639.00000000 NS USD 28174808.05000000 0.378976416324 Long EC CORP US N 1 N N Replimune Group Inc 549300AY704NEIRC4K64 76029N106 2198386.00000000 NS USD 16817652.90000000 0.226212502165 Long EC CORP US N 1 N N Revolution Medicines Inc 549300JU3X0LBCQ65892 76155X100 850768.00000000 NS USD 82737188.00000000 1.112889321176 Long EC CORP US N 1 N N N Rhythm Pharmaceuticals Inc 529900JPNWXQ8DPLA551 76243J105 941162.00000000 NS USD 81852859.14000000 1.100994305542 Long EC CORP US N 1 N N N Rigel Pharmaceuticals Inc 529900KPTNUS5J8K9K66 766559702 708776.00000000 NS USD 19165303.04000000 0.257790500328 Long EC CORP US N 1 N N Rocket Pharmaceuticals Inc 549300R7VV82YUIN4Y93 77313F106 2606982.00000000 NS USD 9332995.56000000 0.125537153780 Long EC CORP US N 1 N N Sana Biotechnology Inc N/A 799566104 6650475.00000000 NS USD 19153368.00000000 0.257629963345 Long EC CORP US N 1 N N Sarepta Therapeutics Inc 549300IKDPIED8J8IG21 803607100 3057030.00000000 NS USD 66520972.80000000 0.894766695036 Long EC CORP US N 1 N N Savara Inc 5493002JO0WM3YMJXG33 805111101 3554970.00000000 NS USD 19410136.20000000 0.261083725731 Long EC CORP US N 1 N N Scholar Rock Holding Corp 549300Z1FLPGL4OWJ459 80706P103 1961965.00000000 NS USD 96450199.40000000 1.297341613030 Long EC CORP US N 1 N N SELLAS Life Sciences Group Inc 549300VZIH50VYURLQ98 81642T209 4689810.00000000 NS USD 19837896.30000000 0.266837482401 Long EC CORP US N 1 N N ARS Pharmaceuticals Inc N/A 82835W108 2213506.00000000 NS USD 17774453.18000000 0.239082323341 Long EC CORP US N 1 N N Sionna Therapeutics Inc N/A 829401108 416630.00000000 NS USD 16702696.70000000 0.224666238261 Long EC CORP US N 1 N N Soleno Therapeutics Inc 5493003LCY77N7FXK844 834203309 1496078.00000000 NS USD 50088691.44000000 0.673737785423 Long EC CORP US N 1 N N Stoke Therapeutics Inc 549300RD25SS2DIJHJ67 86150R107 1125672.00000000 NS USD 36651880.32000000 0.493000634843 Long EC CORP US N 1 N N Summit Therapeutics Inc N/A 86627T108 4866448.00000000 NS USD 92267854.08000000 1.241085320587 Long EC CORP US N 1 N N Syndax Pharmaceuticals Inc 529900OF94TRHKZVBS87 87164F105 2343191.00000000 NS USD 54736941.76000000 0.736260917624 Long EC CORP US N 1 N N N Tango Therapeutics Inc N/A 87583X109 1972571.00000000 NS USD 41266185.32000000 0.555067172071 Long EC CORP US N 1 N N Taysha Gene Therapies Inc N/A 877619106 5638911.00000000 NS USD 25205932.17000000 0.339042375265 Long EC CORP US N 1 N N TG Therapeutics Inc 529900X21UKABN9NJ529 88322Q108 3020301.00000000 NS USD 100334399.22000000 1.349587581325 Long EC CORP US N 1 N N Travere Therapeutics Inc N/A 89422G107 2863192.00000000 NS USD 85065434.32000000 1.144206320571 Long EC CORP US N 1 N N Twist Bioscience Corp 549300T23BL59LCOH584 90184D100 1808036.00000000 NS USD 85917870.72000000 1.155672354038 Long EC CORP US N 1 N N Tyra Biosciences Inc N/A 90240B106 655457.00000000 NS USD 25104003.10000000 0.337671337932 Long EC CORP US N 1 N N Ultragenyx Pharmaceutical Inc 529900EV44GVDN1DCX77 90400D108 3107837.00000000 NS USD 65109185.15000000 0.875776886010 Long EC CORP US N 1 N N N United Therapeutics Corp 5299005C4HZL4UWROC14 91307C102 155530.00000000 NS USD 92226179.40000000 1.240524758795 Long EC CORP US N 1 N N N Vanda Pharmaceuticals Inc 529900AY8VOOQBKJ0O70 921659108 1704031.00000000 NS USD 11774854.21000000 0.158382340824 Long EC CORP US N 1 N N N Vaxcyte Inc 254900M7NMHTGASX8D95 92243G108 1472715.00000000 NS USD 85579468.65000000 1.151120542947 Long EC CORP US N 1 N N N Verastem Inc 549300IY0EFBIU8NQC81 92337C203 2014499.00000000 NS USD 10676844.70000000 0.143613128965 Long EC CORP US N 1 N N Veracyte Inc 529900ESWZRHXOW27Z37 92337F107 1957681.00000000 NS USD 63056905.01000000 0.848171879035 Long EC CORP US N 1 N N Vera Therapeutics Inc N/A 92337R101 1912054.00000000 NS USD 76921932.42000000 1.034668922449 Long EC CORP US N 1 N N N Vericel Corp 54930076YM3PLTDR4B91 92346J108 1116252.00000000 NS USD 35909826.84000000 0.483019350567 Long EC CORP US N 1 N N State Street Global Advisors 549300BZ5TGIFZUZDZ37 857492706 36550.53000000 NS USD 36550.53000000 0.000491637382 Long STIV RF US N 1 N N N State Street Global Advisors 549300BZ5TGIFZUZDZ37 857492706 4700194.36000000 NS USD 4700194.36000000 0.063221826087 Long STIV RF US N 1 N N N Vertex Pharmaceuticals Inc 54930015RAQRRZ5ZGJ91 92532F100 172078.00000000 NS USD 76839710.12000000 1.033562958833 Long EC CORP US N 1 N N N CONTRA VERVE THERAPEUT N/A 925CVR011 900273.00000000 NS USD 567171.99000000 0.007628971520 N/A DE US N 2 N/A N/A Verve Therapeutics, Inc. Verve Therapeutics, Inc. 2099-12-31 XXXX 0.00000000 N N N Viking Therapeutics Inc 529900IVC72YPFA25M37 92686J106 2369189.00000000 NS USD 77093410.06000000 1.036975450372 Long EC CORP US N 1 N N Vir Biotechnology Inc N/A 92764N102 2527795.00000000 NS USD 22649043.20000000 0.304649927335 Long EC CORP US N 1 N N Viridian Therapeutics Inc 549300C775BNYF550E70 92790C104 2667007.00000000 NS USD 52166656.92000000 0.701688283238 Long EC CORP US N 1 N N N Vor BioPharma Inc N/A 929033207 932400.00000000 NS USD 16634016.00000000 0.223742421299 Long EC CORP US N 1 N N Xencor Inc 549300V5IF65437JKG30 98401F105 1422163.00000000 NS USD 17151285.78000000 0.230700163377 Long EC CORP US N 1 N N Zenas Biopharma Inc N/A 98937L105 906255.00000000 NS USD 17717285.25000000 0.238313363453 Long EC CORP US N 1 N N Alkermes PLC N/A 000000000 3050830.00000000 NS USD 107877348.80000000 1.451047012575 Long EC CORP IE N 1 N N N Biohaven Ltd N/A 000000000 3844682.00000000 NS USD 32526009.72000000 0.437503977991 Long EC CORP VG N 1 N N Prothena Corp PLC 5299009ZXQ8NIIJ8OL30 000000000 983448.00000000 NS USD 9559114.56000000 0.128578656960 Long EC CORP IE N 1 N N Roivant Sciences Ltd 549300DL466NY5J6U724 000000000 2864237.00000000 NS USD 79339364.90000000 1.067185555618 Long EC CORP BM N 1 N N N CRISPR Therapeutics AG 506700O6IRRIQLT3W370 000000000 1696801.00000000 NS USD 80716823.57000000 1.085713609100 Long EC CORP CH N 1 N N uniQure NV 724500RPCTZLFYJZ3S98 000000000 1697402.00000000 NS USD 27752522.70000000 0.373296299948 Long EC CORP NL N 1 N N 2026-04-30 SPDR SERIES TRUST Arthur Jensen Arthur Jensen Deputy Treasurer XXXX