X0306 4 2022-10-03 0001061983 CYTOKINETICS INC CYTK 0001846905 Bhanji Muna 350 OYSTER POINT BLVD SOUTH SAN FRANCISCO CA 94080 1 Common Stock 2022-10-03 4 A 0 220 51.11 A 11031 D Shares issued at Reporting Person's election pursuant to Issuer's stock in lieu of cash for all or part of directors' annual base retainer program. Shares are fully vested from the moment of grant. Shares are issued at per share price of $51.11, representing the closing stock price of the Issuer's common stock on October 3, 2022. /s/ John Faurescu, atttorney-in-fact for Ms. Bhanji 2022-10-05