X0306 4 2020-05-01 0 0001061983 CYTOKINETICS INC CYTK 0001288859 Blum Robert I 280 EAST GRAND AVENUE SOUTH SAN FRANCISCO CA 94080 1 1 0 0 President & CEO Common Stock 2020-05-01 4 S 0 5000 14.3356 D 304444 D Common Stock 2083 I by Trust 1 Common Stock 2083 I by Trust 2 5,000 shares disposed of is comprised of: (i) 908 shares of common stock purchased on 10/31/2016 pursuant to the Employee Stock Purchase Plan of Cytokinetics, Incorporated (the ?ESPP?), (ii) 795 shares of common stock purchased on 10/31/2017 pursuant to the ESPP, (iii) 859 shares of common stock purchased on 10/31/2018 pursuant to the ESPP, (iv) 1,117 shares of common stock purchased on 4/28/2017 pursuant to the ESPP, and (v) 1,321 shares of common stock purchased on 4/30/2018 pursuant to the ESPP. Includes 8,846 shares of common stock purchased pursuant to the ESPP. Shares held by The Bridget Blum 2003 Irrevocable Trust. Shares held by The Brittany Blum 2003 Irrevocable Trust. By: John Faurescu, Esq. For: Robert I Blum 2020-05-01