X0306 4 2020-02-27 0 0001061983 CYTOKINETICS INC CYTK 0001288859 Blum Robert I 280 EAST GRAND AVENUE SOUTH SAN FRANCISCO CA 94080 1 1 0 0 President & CEO Common Stock 2020-02-27 4 F 0 13832 13.94 D 193594 D Common Stock 2083 I by Trust 1 Common Stock 2083 I by Trust 2 The reporting person is reporting the withholding of shares of common stock to satisfy the reporting persons withholding obligations in connection with the vesting of Restricted Stock Units vested on 02/27/2020 and does not represent a sale by the reporting person. Includes up to 8,846 shares of common stock purchased pursuant to the Cytokinetics, Incorporated Employee Stock Purchase Plan. Shares held by The Bridget Blum 2003 Irrevocable Trust. Shares held by The Brittany Blum 2003 Irrevocable Trust. Robert I. Blum 2020-03-02