X0303 4 2010-02-24 0 0001061983 CYTOKINETICS INC CYTK 0001316459 Cragg David 280 EAST GRAND AVENUE SOUTH SAN FRANCISCO CA 94080 0 1 0 0 SVP Human Resources Common Stock 10225 D Incentive Stock Option (right to buy) 3.08 2010-02-24 4 A 0 42762 0 A 2010-03-24 2020-02-24 Common Stock 42762 42762 D Non-Qualified Stock Option (right to buy) 3.08 2010-02-24 4 A 0 47238 0 A 2010-03-24 2020-02-24 Common Stock 47238 47238 D Incentive Stock Option (right to buy) 1.85 2009-03-26 2019-02-26 Common Stock 35466 35466 D Incentive Stock Option (right to buy) 3.37 2008-03-29 2018-02-28 Common Stock 20418 20418 D Incentive Stock Option (right to buy) 6.81 2007-04-01 2017-03-14 Common Stock 15184 15184 D Incentive Stock Option (right to buy) 7.15 2006-03-01 2016-03-01 Common Stock 12046 12046 D Incentive Stock Option (right to buy) 9.52 2006-02-01 2015-02-14 Common Stock 34846 34846 D Non-Qualified Stock Option (right to buy) 1.85 2009-03-26 2019-02-26 Common Stock 49534 49534 D Non-Qualified Stock Option (right to buy) 3.37 2008-03-29 2018-02-28 Common Stock 49582 49582 D Non-Qualified Stock Option (right to buy) 6.81 2007-04-01 2017-03-14 Common Stock 34816 34816 D Non-Qualified Stock Option (right to buy) 7.15 2006-03-01 2016-03-01 Common Stock 27954 27954 D Non-Qualified Stock Option (right to buy) 9.52 2006-02-01 2015-02-14 Common Stock 45154 45154 D When the ISO and NQ dated 02/24/2010 are combined for a total grant of 90,000 shares, the option shall vest and become exercisable as to 1,875 shares on 03/24/2010 and the balance of 88,125 divided into equal monthly installments thereafter such that the option shall be 100% vested on 02/24/2014. When the ISO and NQ dated 02/26/2009 are combined for a total grant of 85,000 shares, the option shall vest and become exercisable as to 1,770 shares on 03/26/09 and the balance of 83,230 divided into equal monthly installments thereafter such that the option shall be 100% vested on 02/26/13. When the ISO and NQ dated 02/29/2008 are combined for a total grant of 70,000 shares, the option shall vest and become exercisable as to 1,458 shares on 03/29/08 and the balance of 68,542 divided into equal monthly installments thereafter such that the option shall be 100% vested on 02/29/12. When the ISO and NQ dated 03/14/2007 are combined for a total grant of 50,000 shares, the option shall vest and become exercisable as to 1,042 shares on 04/01/07 and the balance of 48,958 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/01/11. When the ISO and NQ dated 03/01/2006 are combined for a total grant of 40,000 shares, the option shall vest and become exercisable as to 40,000 shares divided into equal monthly installments such that the option shall be 100% vested on 03/01/2010. When the ISO and NQ dated 02/14/05 are combined for a total grant of 80,000 shares, the option shall vest and become exercisable as to 20,000 shares on 02/01/06 and the balance of 60,000 divided into equal monthly installments thereafter such that the option shall be 100% vested on 02/01/09. David W. Cragg 2010-02-26