X0303 4 2010-02-24 0 0001061983 CYTOKINETICS INC CYTK 0001288859 Blum Robert I 280 EAST GRAND AVENUE SOUTH SAN FRANCISCO CA 94080 1 1 0 0 President & CEO Common Stock 18416 D Common Stock 12500 I by Trust 1 Common Stock 12500 I by Trust 2 Incentive Stock Option (right to buy) 3.08 2010-02-24 4 A 0 36834 0 A 2010-03-24 2020-02-24 Common Stock 36834 36834 D Non-Qualified Stock Option (right to buy) 3.08 2010-02-24 4 A 0 233166 0 A 2010-03-24 2020-02-24 Common Stock 233166 233166 D Incentive Stock Option (right to buy) 0.58 2000-01-14 2010-11-14 Common Stock 12 12 D Incentive Stock Option (right to buy) 1.2 2002-07-10 2012-07-10 Common Stock 18833 18833 D Incentive Stock Option (right to buy) 1.2 2003-05-21 2013-05-21 Common Stock 32500 32500 D Incentive Stock Option (right to buy) 1.85 2009-03-26 2019-02-26 Common Stock 50333 50333 D Incentive Stock Option (right to buy) 2 2003-12-18 2013-12-18 Common Stock 27500 27500 D Incentive Stock Option (right to buy) 3.37 2008-03-29 2018-02-28 Common Stock 8334 8334 D Incentive Stock Option (right to buy) 6.59 2005-04-11 2015-04-11 Common Stock 45000 45000 D Incentive Stock Option (right to buy) 6.81 2007-04-01 2017-03-14 Common Stock 22806 22806 D Incentive Stock Option (right to buy) 7.15 2006-03-01 2016-03-01 Common Stock 28494 28494 D Non-Qualified Stock Option (right to buy) 1.2 2002-07-10 2012-07-10 Common Stock 12264 12264 D Non-Qualified Stock Option (right to buy) 1.85 2009-03-26 2019-02-26 Common Stock 224667 224667 D Non-Qualified Stock Option (right to buy) 2 2003-12-18 2013-12-18 Common Stock 48692 48692 D Non-Qualified Stock Option (right to buy) 3.37 2008-03-29 2018-02-28 Common Stock 191666 191666 D Non-Qualified Stock Option (right to buy) 6.81 2007-04-01 2017-03-14 Common Stock 227194 227194 D Non-Qualified Stock Option (right to buy) 7.15 2006-03-01 2016-03-01 Common Stock 71506 71506 D Shares held by The Bridget Blum 2003 Irrevocable Trust. Shares held by The Brittany Blum 2003 Irrevocable Trust. When the ISO and NQ dated 02/24/2010 are combined for a total grant of 270,000 shares, the option shall vest and become exercisable as to 5,625 shares on 03/24/2010 and the balance of 264,375 divided into equal monthly installments thereafter such that the option shall be 100% vested on 02/24/2014. This option is immediately exercisable upon grant and shall vest as to 25,000 shares on 11/14/00 and the balance of 87,500 divided into equal monthly installments thereafter such that the option shall be 100% vested on 11/14/05. When the ISO and NQ dated 07/10/02 are combined for a total grant of 150,000 shares, the option is immediately exercisable upon grant and shall vest as to 2,500 shares on 04/15/02 and the balance of 147,500 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/15/07. This option is immediately exercisable upon grant and shall vest as to 781 shares on 04/01/03 and the balance of 36,719 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/01/07. When the ISO and NQ dated 02/26/2009 are combined for a total grant of 275,000 shares, the option shall vest and become exercisable as to 5,729 shares on 03/26/09 and the balance of 269,271 divided into equal monthly installments thereafter such that the option shall be 100% vested on 02/26/13. When the ISO and NQ dated 12/18/03 are combined for a total grant of 141,925 shares, the option is immediately exercisable upon grant and shall vest as to 2,365 shares on 01/18/04 and the balance of 139,560 divided into equal monthly installments thereafter such that the option shall be 100% vested on 12/18/08. When the ISO and NQ dated 02/29/2008 are combined for a total grant of 200,000 shares, the option shall vest and become exercisable as to 4,166 shares on 03/29/08 and the balance of 195,834 divided into equal monthly installments thereafter such that the option shall be 100% vested on 02/29/12. This option shall vest and become exercisable as to 45,000 shares divided into equal monthly installments such that the option shall be 100% vested on 03/01/2009. When the ISO and NQ dated 03/14/2007 are combined for a total grant of 250,000 shares, the option shall vest and become exercisable as to 5,208 shares on 04/01/07 and the balance of 244,792 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/01/11. When the ISO and NQ dated 03/01/2006 are combined for a total grant of 100,000 shares, the option shall vest and become exercisable as to 100,000 shares divided into equal monthly installments such that the option shall be 100% vested on 03/01/2010. Robert I. Blum 2010-02-26