X0303 4 2010-02-24 0 0001061983 CYTOKINETICS INC CYTK 0001240499 BARBARI SHARON SURREY 280 EAST GRAND AVENUE SOUTH SAN FRANCISCO CA 94080 0 1 0 0 EVP, Finance & CFO Common Stock 14127 D Incentive Stock Option (right to buy) 3.08 2010-02-24 4 A 0 38581 0 A 2010-03-24 2020-02-24 Common Stock 38581 38581 D Non-Qualified Stock Option (right to buy) 3.08 2010-02-24 4 A 0 96419 0 A 2010-03-24 2020-02-24 Common Stock 96419 96419 D Incentive Stock Option (right to buy) 1.85 2009-03-26 2019-02-26 Common Stock 43752 43752 D Incentive Stock Option (right to buy) 3.37 2008-03-29 2018-02-28 Common Stock 27305 27305 D Incentive Stock Option (right to buy) 6.59 2005-04-11 2015-04-11 Common Stock 1031 1031 D Incentive Stock Option (right to buy) 6.81 2007-04-01 2017-03-14 Common Stock 14497 14497 D Incentive Stock Option (right to buy) 7.15 2006-03-01 2016-03-01 Common Stock 16785 16785 D Incentive Stock Option (right to buy) 9.95 2005-09-07 2014-09-15 Common Stock 40200 40200 D Non-Qualified Stock Option (right to buy) 1.85 2009-03-26 2019-02-26 Common Stock 106248 106248 D Non-Qualified Stock Option (right to buy) 3.37 2008-03-29 2018-02-28 Common Stock 95695 95695 D Non-Qualified Stock Option (right to buy) 6.59 2005-04-11 2015-04-11 Common Stock 15469 15469 D Non-Qualified Stock Option (right to buy) 6.81 2007-04-01 2017-03-14 Common Stock 45503 45503 D Non-Qualified Stock Option (right to buy) 7.15 2006-03-01 2016-03-01 Common Stock 43215 43215 D Non-Qualified Stock Option (right to buy) 9.95 2005-09-07 2014-09-15 Common Stock 69800 69800 D When the ISO and NQ dated 02/24/2010 are combined for a total grant of 135,000 shares, the option shall vest and become exercisable as to 2,812 shares on 03/24/2010 and the balance of 132,188 divided into equal monthly installments thereafter such that the option shall be 100% vested on 02/24/2014. When the ISO and NQ dated 02/26/2009 are combined for a total grant of 150,000 shares, the option shall vest and become exercisable as to 3,125 shares on 03/26/09 and the balance of 146,875 divided into equal monthly installments thereafter such that the option shall be 100% vested on 02/26/13. When the ISO and NQ dated 02/29/2008 are combined for a total grant of 125,000 shares, the option shall vest and become exercisable as to 2,604 shares on 03/29/08 and the balance of 122,396 divided into equal monthly installments thereafter such that the option shall be 100% vested on 02/29/12. When the ISO and NQ dated 04/11/05 are combined for a total grant of 16,500 shares, the option shall vest and become exercisable as to 16,500 shares divided into equal monthly installments such that the option shall be 100% vested on 03/01/2009. When the ISO and NQ dated 03/14/2007 are combined for a total grant of 60,000 shares, the option shall vest and become exercisable as to 1,250 shares on 04/01/07 and the balance of 58,750 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/01/11. When the ISO and NQ dated 03/01/2006 are combined for a total grant of 60,000 shares, the option shall vest and become exercisable as to 60,000 shares divided into equal monthly installments such that the option shall be 100% vested on 03/01/2010. When the ISO and NQ dated 09/15/04 are combined for a total grant of 110,000 shares, the option shall vest and become exercisable as to 27,500 shares on 09/07/05 and the balance of 82,500 divided into equal monthly installments thereafter such that the option shall be 100% vested on 09/07/08. Sharon Barbari 2010-02-26