ACCENTURE PLC IRELAND SHS CLASS A G1151C101 1059218 6017599 SH SOLE 5645827 0 371772 ACCENTURE PLC IRELAND SHS CLASS A G1151C101 23235 132000 SH OTR 0 0 132000 ACCENTURE PLC IRELAND SHS CLASS A G1151C101 4337 24639 SH DFND 1 0 24639 0 CHUBB LIMITED COM H1467J104 962650 6872147 SH SOLE 6353801 56119 462227 CHUBB LIMITED COM H1467J104 18911 135000 SH SOLE 0 0 135000 ACTIVISION BLIZZARD INC COM 00507V109 85393 1875542 SH SOLE 1487494 157933 230115 ADDUS HOMECARE CORP COM 006739106 8805 138459 SH SOLE 138459 0 0 AGILENT TECHNOLOGIES INC COM 00846U101 89529 1113823 SH SOLE 882124 94304 137395 ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 15232 83486 SH SOLE 83486 0 0 AMAZON COM INC COM 023135106 1891 1062 SH SOLE 1062 0 0 AMERICAN WOODMARK CORPORATIO COM 030506109 7510 90884 SH SOLE 90884 0 0 AMERICAS CAR MART INC COM 03062T105 27787 304215 SH SOLE 304215 0 0 AMERIS BANCORP COM 03076K108 895 26068 SH SOLE 26068 0 0 AMPHENOL CORP NEW CL A 032095101 133152 1409913 SH SOLE 1117893 118820 173200 ANAPLAN INC COM 03272L108 1339 34016 SH SOLE 34016 0 0 ANSYS INC COM 03662Q105 90241 493902 SH SOLE 390730 41725 61447 ARRAY BIOPHARMA INC COM 04269X105 759 31140 SH SOLE 31140 0 0 ASGN INC COM 00191U102 1341 21119 SH SOLE 21119 0 0 ASML HOLDING N V N Y REGISTRY SHS N07059210 10907 58000 SH OTR 0 0 58000 ASML HOLDING N V N Y REGISTRY SHS N07059210 573278 3048543 SH SOLE 2879479 0 169064 ASML HOLDING N V N Y REGISTRY SHS N07059210 2001 10640 SH DFND 1 0 10640 0 ATRICURE INC COM 04963C209 795 29678 SH SOLE 29678 0 0 AXON ENTERPRISE INC COM 05464C101 1548 28436 SH SOLE 28436 0 0 AZUL S A SPONSR ADR PFD 05501U106 2135 73077 SH SOLE 73077 0 0 BEACON ROOFING SUPPLY INC COM 073685109 9639 299705 SH SOLE 299705 0 0 BIOTELEMETRY INC COM 090672106 1028 16423 SH SOLE 16423 0 0 BIOHAVEN PHARMACTL HLDG CO L COM G11196105 461 8950 SH SOLE 8950 0 0 BIOTELEMETRY INC COM 090672106 1028 16423 SH SOLE 16423 0 0 BLACKLINE INC COM 09239B109 1133 24466 SH SOLE 24466 0 0 BOSTON SCIENTIFIC CORP COM 101137107 146738 3823315 SH SOLE 3027852 323623 471840 BRIGHT HORIZONS FAM SOL IN D COM 109194100 1814 14274 SH SOLE 14274 0 0 BRINKS CO COM 109696104 1389 18422 SH SOLE 18422 0 0 BROWN & BROWN INC COM 115236101 8828 299169 SH SOLE 299169 0 0 BRUKER CORP COM 116794108 1624 42254 SH SOLE 42254 0 0 CABOT MICROELECTRONICS CORP COM 12709P103 11253 100506 SH SOLE 100506 0 0 CALLAWAY GOLF CO COM 131193104 932 58508 SH SOLE 58508 0 0 CANADIAN NATL RY CO COM 136375102 116320 1299957 SH SOLE 1010522 117790 171645 CANADIAN PAC RY LTD COM 13645T100 21839 106000 SH OTR 0 0 106000 CANADIAN PAC RY LTD COM 13645T100 995102 4829888 SH SOLE 4597304 0 232584 CANADIAN PAC RY LTD COM 13645T100 4054 19677 SH DFND 1 0 19677 0 CASEYS GEN STORES INC COM 147528103 1081 8394 SH SOLE 8394 0 0 CASS INFORMATION SYS INC COM 14808P109 15556 328870 SH SOLE 328870 0 0 CENTENNIAL RESOURCE DEV INC CL A 15136A102 791 90012 SH SOLE 90012 0 0 CHARLES RIV LABS INTL INC COM 159864107 1459 10042 SH SOLE 10042 0 0 CHUBB LIMITED COM H1467J104 962650 6872147 SH SOLE 6353801 56119 462227 CHUBB LIMITED COM H1467J104 18911 135000 SH OTR 0 0 135000 CHUBB LIMITED COM H1467J104 3510 25056 SH DFND 1 0 25056 0 CONTROL4 CORP COM 21240D107 3486 205900 SH SOLE 205900 0 0 COOPER COS INC COM NEW 216648402 158512 535205 SH SOLE 423779 45341 66085 CORE LABORATORIES N V COM N22717107 209071 3033095 SH SOLE 2835101 0 197994 CORE LABORATORIES N V COM N22717107 4618 67000 SH OTR 0 0 67000 CORE LABORATORIES N V COM N22717107 924 13398 SH DFND 1 0 13398 0 COSTCO WHSL CORP NEW COM 22160K105 168765 696971 SH SOLE 552649 58702 85620 CRANE CO COM 224399105 12383 146335 SH SOLE 146335 0 0 CREDICORP LTD COM G2519Y108 3348 13953 SH SOLE 13953 0 0 CROWN CASTLE INTL CORP NEW COM 22822V101 121876 952155 SH SOLE 755441 80039 116675 CUBIC CORP COM 229669106 1298 23091 SH SOLE 23091 0 0 DAVE & BUSTERS ENTMT INC COM 238337109 1167 23394 SH SOLE 23394 0 0 DORMAN PRODUCTS INC COM 258278100 9619 109200 SH SOLE 109200 0 0 DYCOM INDS INC COM 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27807 SH SOLE 27807 0 0 FLIR SYS INC COM 302445101 5354 112522 SH SOLE 112522 0 0 GLOBANT S A COM L44385109 2899 40599 SH SOLE 40599 0 0 GRACO INC COM 384109104 86914 1755134 SH SOLE 1405972 141224 207938 GREEN DOT CORP CL A 39304D102 1432 23618 SH SOLE 23618 0 0 GRUPO AEROPORTUARIO DEL SURE SPON ADR SER B 40051E202 2923 18069 SH SOLE 18069 0 0 HALOZYME THERAPEUTICS INC COM 40637H109 515 31997 SH SOLE 31997 0 0 HDFC BANK LTD SPONSORED ADS 40415F101 20632 178000 SH OTR 0 0 178000 HDFC BANK LTD SPONSORED ADS 40415F101 1101499 9503053 SH SOLE 8736761 108984 657308 HDFC BANK LTD SPONSORED ADS 40415F101 3823 32984 SH DFND 1 0 32984 0 HEMISPHERE MEDIA GROUP INC CL A 42365Q103 9065 642895 SH SOLE 642895 0 0 HERON THERAPEUTICS INC COM 427746102 422 17267 SH SOLE 17267 0 0 HFF INC CL A 40418F108 11110 232674 SH SOLE 232674 0 0 ICON PLC SHS G4705A100 9287 68000 SH OTR 0 0 68000 ICON PLC SHS G4705A100 442204 3237696 SH SOLE 3050020 0 187676 ICON PLC SHS G4705A100 1698 12433 SH DFND 1 0 12433 0 ICU MED INC COM 44930G107 1512 6316 SH SOLE 6316 0 0 ILLUMINA INC COM 452327109 70937 228321 SH SOLE 180956 19275 28090 INGEVITY CORP COM 45688C107 1548 14657 SH SOLE 14657 0 0 INOGEN INC COM 45780L104 609 6383 SH SOLE 6383 0 0 INPHI CORP COM 45772F107 1384 31637 SH SOLE 31637 0 0 SANFILIPPO JOHN B & SON INC COM 800422107 6801 94630 SH SOLE 94630 0 0 JOHN BEAN TECHNOLOGIES CORP COM 477839104 1849 20121 SH SOLE 20121 0 0 JONES LANG LASALLE INC COM 48020Q107 17379 112717 SH SOLE 112717 0 0 KURA ONCOLOGY INC COM 50127T109 320 19288 SH SOLE 19288 0 0 LIGAND PHARMACEUTICALS INC COM NEW 53220K504 359 2854 SH SOLE 2854 0 0 LIVANOVA PLC SHS G5509L101 1317 13545 SH SOLE 13545 0 0 LOGMEIN INC COM 54142L109 1109 13846 SH SOLE 13846 0 0 MANHATTAN ASSOCS INC COM 562750109 20608 373952 SH SOLE 373952 0 0 MARRIOTT VACTINS WORLDWID CO COM 57164Y107 1638 17512 SH SOLE 17512 0 0 MERCADOLIBRE INC COM 58733R102 177785 350156 SH SOLE 278817 29034 42305 MERCURY SYS INC COM 589378108 1672 26097 SH SOLE 26097 0 0 MERIT MED SYS INC COM 589889104 1612 26071 SH SOLE 26071 0 0 METTLER TOLEDO INTERNATIONAL COM 592688105 20244 28000 SH OTR 0 0 28000 METTLER TOLEDO INTERNATIONAL COM 592688105 1057412 1462535 SH SOLE 1349429 13760 99346 METTLER TOLEDO INTERNATIONAL COM 592688105 3825 5290 SH DFND 1 0 5290 0 MOELIS & CO CL A 60786M105 1176 28252 SH SOLE 28252 0 0 NATUS MEDICAL INC DEL COM 639050103 10233 403183 SH SOLE 403183 0 0 NETFLIX INC COM 64110L106 110942 311145 SH SOLE 246521 26289 38335 NICE LTD SPONSORED ADR 653656108 205 1671 SH SOLE 1671 0 0 NLIGHT INC COM 65487K100 1063 47709 SH SOLE 47709 0 0 OASIS PETE INC NEW COM 674215108 591 97811 SH SOLE 97811 0 0 OMNICELL INC COM 68213N109 1740 21533 SH SOLE 21533 0 0 ORBCOMM INC COM 68555P100 720 106275 SH SOLE 106275 0 0 OSHKOSH CORP COM 688239201 1238 16488 SH SOLE 16488 0 0 PENUMBRA INC COM 70975L107 1226 8340 SH SOLE 8340 0 0 PLANET FITNESS INC CL A 72703H101 1785 25971 SH SOLE 25971 0 0 PRIMERICA INC COM 74164M108 1512 12380 SH SOLE 12380 0 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82509L107 24588 119000 SH OTR 0 0 119000 SHOPIFY INC CL A 82509L107 1334698 6459671 SH SOLE 5961722 65098 432851 SHOPIFY INC CL A 82509L107 4638 22445 SH DFND 1 0 22445 0 SHUTTERSTOCK INC COM 825690100 1252 26859 SH SOLE 26859 0 0 SP PLUS CORP COM 78469C103 17427 510745 SH SOLE 510745 0 0 STERIS PLC SHS USD G8473T100 302656 2382799 SH SOLE 2107055 98727 177017 STRYKER CORP COM 863667101 118161 598221 SH SOLE 473636 50695 73890 SURGERY PARTNERS INC COM 86881A100 717 63547 SH SOLE 63547 0 0 SYNOPSYS INC COM 871607107 321 2790 SH SOLE 2790 0 0 TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 3415 83367 SH DFND 1 0 83367 0 TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 18432 450000 SH OTR 0 0 450000 TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 994444 24278439 SH SOLE 22416151 238441 1623847 TELADOC HEALTH INC COM 87918A105 843 15163 SH SOLE 15163 0 0 P T TELEKOMUNIKASI INDONESIA SPONSORED ADR 715684106 2732 99479 SH SOLE 99479 0 0 TETRA TECH INC NEW COM 88162G103 1122 18839 SH SOLE 18839 0 0 TEXAS ROADHOUSE INC COM 882681109 1328 21362 SH SOLE 21362 0 0 THERMON GROUP HLDGS INC COM 88362T103 13327 543728 SH SOLE 543728 0 0 ULTIMATE SOFTWARE GROUP INC COM 90385D107 343 1040 SH SOLE 1040 0 0 UNIFIRST CORP MASS COM 904708104 19479 126901 SH SOLE 126901 0 0 UNIVERSAL FST PRODS INC COM 913543104 1460 48822 SH SOLE 48822 0 0 VERISK ANALYTICS INC COM 92345Y106 136946 1029676 SH SOLE 816676 86660 126340 VIRTUS INVT PARTNERS INC COM 92828Q109 12213 125198 SH SOLE 125198 0 0 VISA INC COM CL A 92826C839 170372 1090798 SH SOLE 865516 91667 133615 WESCO INTL INC COM 95082P105 10767 203117 SH SOLE 203117 0 0 WEST PHARMACEUTICAL SVSC INC COM 955306105 123658 1122116 SH SOLE 887417 94960 139739 WINGSTOP INC COM 974155103 1621 21323 SH SOLE 21323 0 0 WIX COM LTD SHS M98068105 2788 23070 SH SOLE 23070 0 0 WNS HOLDINGS LTD SPON ADR 92932M101 1367 25668 SH SOLE 25668 0 0 WOODWARD INC COM 980745103 1643 17306 SH SOLE 17306 0 0 WORKDAY INC CL A 98138H101 675 3500 SH SOLE 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