Royalty Agreement - Additional Information (Detail) - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2016	Sep. 30, 2012
Royalty Agreement [Line Items]
Revenue participation right payments, rate	6.75%
Revenue participation right payments, term	10 years from the date of first commercial sale
Maximum term of revenue participation right payments	10 years
Royalty Agreement [Member]
Royalty Agreement [Line Items]
Revenue participation right payments		$ 25.0
Fair value of warrants issued in connection with participation agreement	$ 3.1