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Stockholders' Equity - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
May 28, 2021
Feb. 24, 2021
Jan. 01, 2020
Jan. 31, 2017
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Jul. 30, 2020
Stockholders Equity [Line Items]                  
Common stock, shares outstanding         37,486,177   37,424,863    
Convertible Preferred Stock, Shares Issued upon Conversion               18,811,552  
Preferred stock, shares authorized         10,000,000        
Shares Issued         0        
Preferred stock, shares outstanding         10,248   10,248    
Share of common stock value         $ 25,000        
Weighted average exercise price         $ 6.13   $ 7.33    
Stock reserved for future grant         8,240,586   6,429,819    
Stock-based compensation         $ 1,772,000 $ 644,000      
Stock option plan weighted average vesting period         9 years 1 month 6 days   8 years 10 months 24 days    
Twenty Thousand and Sixteen Equity Incentive Plan [Member]                  
Stockholders Equity [Line Items]                  
Options granted period         10 years        
2021 Equity Incentive Plan [Member]                  
Stockholders Equity [Line Items]                  
Common stock available for issuance automatic increase period     10 years            
Shares of common stock available for issuance     3,771,428   2,628,571        
Shares Available for Issuance         985,358        
Shares Available for Future Grant         84,591        
Purchase price of a share as a percentage of fair market value         100.00%        
Stock Options Granted         10 years        
Percentage Of Nonqualified Options Exercisable Price Of Fair Market Value Of Common Stock         100.00%        
Weighted average exercise price         $ 28.18        
2021 Inducement Plan [Member]                  
Stockholders Equity [Line Items]                  
Shares of common stock available for issuance         515,000        
Stock reserved for future grant         1,000,000        
Stock Options [Member]                  
Stockholders Equity [Line Items]                  
Stock-based compensation         $ 1,600,000 500,000      
Stock option plan weighted average vesting period         3 years        
Unrecognised compensation expense related to unvested units         $ 19,200,000        
Incentive Stock Options [Member] | Twenty Thousand and Sixteen Equity Incentive Plan [Member]                  
Stockholders Equity [Line Items]                  
Percentage of exercise price fair value       100.00%          
Nonqualified Options [Member] | Twenty Thousand and Sixteen Equity Incentive Plan [Member]                  
Stockholders Equity [Line Items]                  
Percentage of exercise price fair value       85.00%          
Restricted Stock Units [Member]                  
Stockholders Equity [Line Items]                  
Stock reserved for future grant         692,408   745,668    
Stock-based compensation         $ 200,000 $ 100,000      
Unrecognised compensation expense related to unvested units         $ 2,500,000        
Restricted Stock units plan weighted average vesting period         3 years 2 months 12 days        
Minimum [Member] | Twenty Thousand and Sixteen Equity Incentive Plan [Member]                  
Stockholders Equity [Line Items]                  
Options,vesting period         0 years        
Maximum [Member]                  
Stockholders Equity [Line Items]                  
Stock Options Granted         4 years        
Maximum [Member] | Twenty Thousand and Sixteen Equity Incentive Plan [Member]                  
Stockholders Equity [Line Items]                  
Options,vesting period         4 years        
Series E and Series F Convertible Preferred Stock [Member]                  
Stockholders Equity [Line Items]                  
Preferred stock, payment to stock holders in the event of liquidation, dissolution or winding up preference per share         $ 0.0001        
Percentage of outstanding common stock         9.98%        
Shares issuable upon conversion of preferred stock [Member]                  
Stockholders Equity [Line Items]                  
Stock reserved for future grant         292,799   292,799    
Series E Convertible Preferred Stock [Member]                  
Stockholders Equity [Line Items]                  
Price per common share         $ 500        
Preferred stock, shares outstanding         1,915        
Convertible share price per share         $ 17.50        
Series F Convertible Preferred Stock [Member]                  
Stockholders Equity [Line Items]                  
Price per common share         $ 600        
Preferred stock, shares outstanding         8,333        
Convertible share price per share         $ 21.00        
Warrant [Member] | Preferred Stock Warrants [Member]                  
Stockholders Equity [Line Items]                  
Class of warrant or right, exercise price of warrants or rights                 $ 0.6055
Issue of warrants exercisable                 206,440
Warrant [Member] | Preferred Stock Warrants [Member] | Silicon Valley Bank [Member]                  
Stockholders Equity [Line Items]                  
Class of warrant or right, exercise price of warrants or rights                 $ 5.42
Issue of warrants exercisable                 23,100
Common Stock [Member]                  
Stockholders Equity [Line Items]                  
Shares Issued         37,486 37,036,000 37,425 906,000  
Stock issued during period           5,173,000      
Stock Issued During Period, Shares, New Issues           12,012,000      
Common Stock [Member] | Common Warrants [Member]                  
Stockholders Equity [Line Items]                  
Class of warrant or right, exercise price of warrants or rights         $ 0.09     $ 0.09  
Class of warrant or right issued in period of warrants or rights         250,323     250,323  
Class of warrant or right issued remain unexercised         86,209        
Warrant expiration period         7 years        
Employee Stock Purchase Plan [Member]                  
Stockholders Equity [Line Items]                  
Shares Available for Future Grant         60,948        
Purchase price of a share as a percentage of fair market value         85.00%        
Duration of offering period         12 months        
Duration of each purchase period         6 months        
Stock reserved for future grant         60,948   60,948    
Private Placement [Member] | Common Stock [Member]                  
Stockholders Equity [Line Items]                  
Proceeds from issuance initial public offering   $ 65,000,000.0              
Adjustments to additional paid in capital stock issuance costs   $ 2,700,000              
Stock Issued During Period, Shares, New Issues   12,012,369              
Sales Agreement [Member]                  
Stockholders Equity [Line Items]                  
Common stock par value $ 0.0001                
Legal and accounting cost         $ 100,000        
Sales Agreement [Member] | Maximum [Member]                  
Stockholders Equity [Line Items]                  
Potential sales of common stock $ 50,000,000.0