Organization and Basis of Presentation - Additional Information (Detail) $ in Thousands		1 Months Ended	3 Months Ended
	Feb. 24, 2021	Feb. 28, 2021 USD ($)	Mar. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Nov. 04, 2021 USD ($)
Accumulated deficit			$ (176,223)	$ (165,677)
Cash and cash equivalents			92,199	$ 103,554
Working capital			$ 87,600
Gross proceeds from private placement		$ 65,000
Reverse stock split	3.5-for-one
Percentage of outstanding common stock of combined company			86.00%
Conversion ratio			0.1119
Line of credit maximum borrowing amount					$ 50,000
Line of Credit Facility, Remaining Borrowing Capacity					45,000
Silicon Valley Bank ("SVB") and Oxford Finance LLC ("Oxford") [Member]
Line of credit maximum borrowing amount					50,000
Line of Credit Facility, Current Borrowing Capacity					5,000
Line of Credit Facility, Remaining Borrowing Capacity					45,000
Tranche Two [Member]
Line of Credit Facility, Remaining Borrowing Capacity					25,000
Tranche Two [Member] | Silicon Valley Bank ("SVB") and Oxford Finance LLC ("Oxford") [Member]
Line of Credit Facility, Remaining Borrowing Capacity					20,000
Tranche Three [Member] | Silicon Valley Bank ("SVB") and Oxford Finance LLC ("Oxford") [Member]
Line of Credit Facility, Remaining Borrowing Capacity					$ 25,000
Royalty Purchase Agreement [member]
Upfront payment received			$ 13,500