<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001466153</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>2</amendmentNo>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>02/27/2026</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001060955</issuerCik>
        <issuerName>ICON plc</issuerName>
        <issuerCusip>G4705A100</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <street1 xmlns="http://www.sec.gov/edgar/common">South County Buisness Park</street1>
          <city xmlns="http://www.sec.gov/edgar/common">Leopardstown, Dublin 18</city>
          <stateOrCountry xmlns="http://www.sec.gov/edgar/common">L2</stateOrCountry>
          <zipCode xmlns="http://www.sec.gov/edgar/common">D18 X5R3</zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Artisan Partners Asset Management Inc.</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>8131735</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>8361303</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>8361303</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>10.9</classPercent>
      <typeOfReportingPerson>HC</typeOfReportingPerson>
      <comments>
(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Artisan Partners Holdings LP</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>8131735</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>8361303</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>8361303</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>10.9</classPercent>
      <typeOfReportingPerson>HC</typeOfReportingPerson>
      <comments>
(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Artisan Investments GP LLC</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>8131735</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>8361303</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>8361303</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>10.9</classPercent>
      <typeOfReportingPerson>HC</typeOfReportingPerson>
      <comments>
(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Artisan Partners Limited Partnership</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>8131735</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>8361303</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>8361303</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>10.9</classPercent>
      <typeOfReportingPerson>IA</typeOfReportingPerson>
      <comments>
(e) Artisan Partners Limited Partnership is an investment adviser registered under section 203 of the Investment Advisers Act of 1940.

(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Artisan Partners Funds, Inc.</reportingPersonName>
      <citizenshipOrOrganization>WI</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>6449466</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>6449466</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>6449466</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>8.4</classPercent>
      <typeOfReportingPerson>IC</typeOfReportingPerson>
      <comments>
(d) Artisan Partners Funds, Inc. is an Investment Company under section 8 of the Investment Company Act.</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>ICON plc</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>South County Business Park, Leopardstown, Dublin 18, D18 X5R3, Ireland</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Artisan Partners Asset Management Inc. ("APAM")
Artisan Partners Holdings LP ("Artisan Holdings")
Artisan Investments GP LLC ("Artisan Investments")
Artisan Partners Limited Partnership ("APLP")
Artisan Partners Funds, Inc. ("Artisan Funds")</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>APAM, Artisan Holdings, Artisan Investments, APLP, and Artisan Funds are all located at:

875 East Wisconsin Avenue, Suite 800
Milwaukee, WI 53202</principalBusinessOfficeOrResidenceAddress>
        <citizenship>APAM is a Delaware corporation; Artisan Holdings is a Delaware limited partnership; Artisan Investments is a Delaware limited liability company; APLP is a Delaware limited partnership; Artisan Funds is a Wisconsin corporation</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
        <typeOfPersonFiling>IV</typeOfPersonFiling>
        <typeOfPersonFiling>IA</typeOfPersonFiling>
        <typeOfPersonFiling>HC</typeOfPersonFiling>
      </item3>
      <item4>
        <amountBeneficiallyOwned>8,361,303</amountBeneficiallyOwned>
        <classPercent>10.9% (based on 79,359,932 shares outstanding as of 11/03/2025)</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>None</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>8,131,735</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>None</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>8,361,303</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>N</notApplicableFlag>
        <ownershipMoreThan5PercentOnBehalfOfAnotherPerson>The shares reported herein have been acquired on behalf of discretionary clients of APLP; as reported herein, APLP holds 8,361,303 shares, including 6,449,466 shares on behalf of Artisan Funds. Persons other than APLP are entitled to receive all dividends from, and proceeds from the sale of, those shares.</ownershipMoreThan5PercentOnBehalfOfAnotherPerson>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <exhibitInfo>Exhibit Index

Exhibit 1 - Joint Filing Agreement dated 3/6/2026 Artisan Partners Asset Management Inc., Artisan Partners Holdings LP, Artisan Investments GP LLC, Artisan Partners Limited Partnership, and Artisan Partners Funds, Inc.
</exhibitInfo>
    <signatureInformation>
      <reportingPersonName>Artisan Partners Asset Management Inc.</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Gregory K. Ramirez</signature>
        <title>Gregory K. Ramirez, Executive Vice President of Artisan Partners Asset Management Inc.</title>
        <date>03/06/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Artisan Partners Holdings LP</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Gregory K. Ramirez</signature>
        <title>Gregory K. Ramirez, Executive Vice President of Artisan Partners Asset Management Inc., as the general partner of Artisan Partners Holdings LP</title>
        <date>03/06/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Artisan Investments GP LLC</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Gregory K. Ramirez</signature>
        <title>Gregory K. Ramirez, Vice President of Artisan Investments GP LLC</title>
        <date>03/06/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Artisan Partners Limited Partnership</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Gregory K. Ramirez</signature>
        <title>Gregory K. Ramirez, Vice President of Artisan Investments GP LLC, as the general partner of Artisan Partners Limited Partnership</title>
        <date>03/06/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Artisan Partners Funds, Inc.</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Gregory K. Ramirez</signature>
        <title>Gregory K. Ramirez, President and Chief Executive Officer of Artisan Partners Funds, Inc.</title>
        <date>03/06/2026</date>
      </signatureDetails>
    </signatureInformation>
  </formData>

</edgarSubmission>
