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Property, Plant and Equipment, net (Tables)
12 Months Ended
Dec. 31, 2013
Property Plant and Equipment Net
   
December 31,
   
December 31,
 
   
2013
   
2012
 
   
(in thousands)
 
Cost
           
Land
  $ 3,464     $ 3,325  
Building
    96,450       94,395  
Computer equipment and software
    212,019       189,455  
Office furniture and fixtures
    68,268       66,351  
Laboratory equipment
    29,678       32,724  
Leasehold improvements
    15,304       10,482  
Motor vehicles
    56       69  
      425,239       396,801  
Less accumulated depreciation and asset write off
    (264,409 )     (228,428 )
                 
Property, plant and equipment (net)
  $ 160,830     $ 168,373