Property And Equipment (Details) (USD $)	12 Months Ended
Dec. 31, 2011	Dec. 31, 2010	Dec. 31, 2009
Property And Equipment [Abstract]
Leasehold improvements	$ 18,818,000	$ 12,540,000
Laboratory equipment	15,377,000	13,763,000
Computers and office equipment	5,590,000	4,419,000
Furniture and fixtures	4,691,000	3,131,000
Property and Equipment, Gross	44,476,000	33,853,000
Less: accumulated depreciation and amortization	(24,824,000)	(21,542,000)
Total	19,652,000	12,311,000
Depreciation and amortization expenses	$ 3,900,000	$ 3,600,000	$ 3,300,000

The cumulative amount of depreciation, depletion and amortization (related to property, plant and equipment, but not including land) that has been recognized in the income statement.

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The current period expense charged against earnings on long-lived, physical assets not used in production, and which are not intended for resale, to allocate or recognize the cost of such assets over their useful lives; or to record the reduction in book value of an intangible asset over the benefit period of such asset; or to reflect consumption during the period of an asset that is not used in production.

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- Definition

Gross amount, at the balance sheet date, of long-lived physical assets used in the normal conduct of business and not intended for resale. This can include land, buildings, machinery and equipment, and other types of furniture and equipment including, but not limited to, office equipment, furniture and fixtures, and computer equipment and software.

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- Definition

Tangible assets that are held by an entity for use in the production or supply of goods and services, for rental to others, or for administrative purposes and that are expected to provide economic benefit for more than one year; net of accumulated depreciation. Examples include land, buildings, machinery and equipment, and other types of furniture and equipment including, but not limited to, office equipment, furniture and fixtures, and computer equipment and software.

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