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Acquisition of Cascadian - Schedule of Purchase Price Allocation of Assets Acquired and Liabilities Assumed (Detail) - USD ($)
$ in Thousands
Sep. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Business Acquisition [Line Items]      
Goodwill $ 251,017   $ 0
Cascadian Therapeutics [Member]      
Business Acquisition [Line Items]      
Cash and cash equivalents   $ 15,919  
Short-term and long-term investments   66,491  
Prepaid expenses and other assets   2,215  
Property and equipment   566  
In-process research and development   300,000  
Goodwill   251,017  
Accounts payable and accrued liabilities   (22,138)  
Total purchase price   $ 614,070