Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the incorporation by reference in Registration Statement No. 333-106661 on Form S-8 of First BanCorp. of our report dated June 26, 2025 appearing in this Annual Report on Form 11-K of The FirstBank 401(k) Retirement Plan for Residents of the U.S. Virgin Islands and the United States of America for the year ended December 31, 2024.

/s/ Crowe LLP

Chicago, Illinois

June 26, 2025