Exhibit 21

List of Subsidiaries

As of December 31, 2022 the Company has these wholly-owned subsidiaries located throughout the world, as follows:

  1.Mannatech Australia Pty Limited

  2.Mannatech Japan, G.K.

  3.Mannatech Korea Co., Ltd.

  4.Mannatech Limited (a New Zealand Company)

  5.Mannatech Limited (a UK Company)

  6.Mannatech Taiwan Corporation

  7.Mannatech Payment Services Incorporated

  8.Mannatech Products Company Inc.

  9.Internet Health Group, Inc.

10.Mannatech (International) Limited

11.Mannatech, Incorporated Malaysia Sdn. Bhd.

12.Mannatech Singapore Pte. Ltd.

13.Mannatech Canada Corporation

14.Mannatech South Africa (Pty) Ltd

15.Mannatech Bermuda Holdings Limited

16.Mannatech Denmark ApS

17.Mannatech (Gibraltar) Holdings Limited

18.Mannatech Swiss Holdings GmbH

19.Mannatech Swiss International GmbH

20.Mannatech Malaysia Trading Co. Sdn. Bhd.

21.Mannatech Norge A/S

22.Mannatech Sverige AB

23.MTEX Mexico SRL CV

24.MTEX Mexico Services SRL CV

25.Mannatech Cyprus Limited

26.Mannatech Ukraine LLC

27.MTEX Hong Kong Limited

28.Mannatech RUS Ltd.

29.Meitai Daily Necessity & Health Products Co., Ltd.

30.Meitai Daily Necessity & Health Products Co., Ltd. Guangzhou Branch

31.Mannatech Netherlands B.V.

32.Mannatech Products Hong Kong Limited

33.New Economy Marketing Opportunities, LLC