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0001172661-23-001310.txt : 20230214 0001172661-23-001310.hdr.sgml : 20230214 20230214160723 ACCESSION NUMBER: 0001172661-23-001310 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20221231 FILED AS OF DATE: 20230214 DATE AS OF CHANGE: 20230214 EFFECTIVENESS DATE: 20230214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: ORBIMED ADVISORS LLC CENTRAL INDEX KEY: 0001055951 IRS NUMBER: 133976876 STATE OF INCORPORATION: DE FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-06774 FILM NUMBER: 23629087 BUSINESS ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 BUSINESS PHONE: (212) 739-6400 MAIL ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false true false 0001055951 XXXXXXXX 12-31-2022 12-31-2022 false ORBIMED ADVISORS LLC

601 Lexington Avenue 54th Floor New York NY 10022

13F HOLDINGS REPORT 028-06774 000118608 801-61046 N Sven H. Borho Member 212-739-6400 /s/ Sven H. Borho New York NY 02-14-2023 1 116 5227458389 1 0001157524 028-10410 000120188 801-61952 ORBIMED CAPITAL LLC INFORMATION TABLE 2 infotable.xml 2SEVENTY BIO INC COMMON STOCK 901384107 9756981 1041300 SH DFND 337000 0 704300 89BIO INC COM 282559103 46577402 3658869 SH SOLE 3658869 0 0 ABCELLERA BIOLOGICS INC COM 00288U106 42351180 4180768 SH SOLE 4180768 0 0 ACLARIS THERAPEUTICS INC COM 00461U105 43445336 2758434 SH DFND 488400 0 2270034 ACUTUS MED INC COM 005111109 3045644 2648386 SH SOLE 2648386 0 0 ADICET BIO INC COM 007002108 66577432 7447140 SH SOLE 7447140 0 0 AEGLEA BIOTHERAPEUTICS INC COM 00773J103 808570 1797221 SH SOLE 1797221 0 0 AEROVATE THERAPEUTICS INC COM 008064107 22254522 759540 SH DFND 215800 0 543740 ALPINE IMMUNE SCIENCES INC COM 02083G100 29999701 4081592 SH SOLE 4081592 0 0 ALX ONCOLOGY HLDGS INC COM 00166B105 32356170 2871000 SH DFND 605000 0 2266000 AMICUS THERAPEUTICS INC COM 03152W109 6300360 516000 SH DFND 72700 0 443300 AMNEAL PHARMACEUTICALS INC COM STK CL A 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