0001172661-22-001998.txt : 20220815 0001172661-22-001998.hdr.sgml : 20220815 20220815163154 ACCESSION NUMBER: 0001172661-22-001998 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20220630 FILED AS OF DATE: 20220815 DATE AS OF CHANGE: 20220815 EFFECTIVENESS DATE: 20220815 FILER: COMPANY DATA: COMPANY CONFORMED NAME: ORBIMED ADVISORS LLC CENTRAL INDEX KEY: 0001055951 IRS NUMBER: 133976876 STATE OF INCORPORATION: DE FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-06774 FILM NUMBER: 221166076 BUSINESS ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 BUSINESS PHONE: (212) 739-6400 MAIL ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001055951 XXXXXXXX 06-30-2022 06-30-2022 false ORBIMED ADVISORS LLC

601 Lexington Avenue 54th Floor New York NY 10022

13F HOLDINGS REPORT 028-06774 N Sven H. Borho 212-739-6400 /s/ Sven H. Borho New York NY 08-15-2022 1 145 5518815 1 0001157524 028-10410 ORBIMED CAPITAL LLC INFORMATION TABLE 2 infotable.xml 89BIO INC COM 282559103 11782 3658869 SH SOLE 3658869 0 0 9 METERS BIOPHARMA INC COM 654405109 2218 8505729 SH SOLE 8505729 0 0 ABBVIE INC COM 00287Y109 122497 799800 SH DFND 28000 0 771800 ABCELLERA BIOLOGICS INC COM 00288U106 44525 4180768 SH SOLE 4180768 0 0 ABCELLERA BIOLOGICS INC COM 00288U106 2663 250000 SH Call DFND 69000 0 181000 ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 3994 1584845 SH DFND 178735 0 1406110 ACLARIS THERAPEUTICS INC COM 00461U105 32464 2325500 SH DFND 420400 0 1905100 ACUTUS MED INC COM 005111109 2966 2648386 SH SOLE 2648386 0 0 ADAGIO THERAPEUTICS INC COM 00534A102 16584 5056000 SH SOLE 5056000 0 0 ADICET BIO INC COM 007002108 108728 7447141 SH SOLE 7447141 0 0 AEGLEA BIOTHERAPEUTICS INC COM 00773J103 908 1797221 SH SOLE 1797221 0 0 AEROVATE THERAPEUTICS INC COM 008064107 7480 478579 SH DFND 124779 0 353800 ALPINE IMMUNE SCIENCES INC 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