0001172661-20-000859.txt : 20200214 0001172661-20-000859.hdr.sgml : 20200214 20200214162739 ACCESSION NUMBER: 0001172661-20-000859 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20191231 FILED AS OF DATE: 20200214 DATE AS OF CHANGE: 20200214 EFFECTIVENESS DATE: 20200214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: ORBIMED ADVISORS LLC CENTRAL INDEX KEY: 0001055951 IRS NUMBER: 133976876 STATE OF INCORPORATION: DE FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-06774 FILM NUMBER: 20620612 BUSINESS ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 BUSINESS PHONE: (212) 739-6400 MAIL ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001055951 XXXXXXXX 12-31-2019 12-31-2019 false ORBIMED ADVISORS LLC

601 Lexington Avenue 54th Floor New York NY 10022

13F HOLDINGS REPORT 028-06774 N Sven H. Borho 212-739-6400 /s/ Sven H. Borho New York NY 02-14-2020 1 136 7004336 1 0001157524 028-10410 ORBIMED CAPITAL LLC INFORMATION TABLE 2 infotable.xml 89BIO INC COM 282559103 105277 4004442 SH SOLE 4004442 0 0 ABBOTT LABS COM 002824100 62114 715100 SH DFND 1 194000 0 521100 ACADIA PHARMACEUTICALS INC COM 004225108 4113 96143 SH SOLE 0 0 96143 ACCELERON PHARMA INC COM 00434H108 5700 107500 SH SOLE 0 0 107500 ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 1621 1350655 SH SOLE 1350655 0 0 ADVERUM BIOTECHNOLOGIES INC COM 00773U108 50022 4342190 SH DFND 1 398100 0 3944090 AEGLEA BIOTHERAPEUTICS INC COM 00773J103 21893 2865524 SH SOLE 2865524 0 0 AERPIO PHARMACEUTICALS INC COM 00810B105 3238 5193946 SH SOLE 5193946 0 0 ALCON INC ORD SHS H01301128 19925 351380 SH DFND 1 125800 0 225580 ALECTOR INC COM 014442107 189322 10987944 SH DFND 1 10930344 0 57600 ALEXION PHARMACEUTICALS INC COM 015351109 179809 1662585 SH DFND 1 285200 0 1377385 ALPINE IMMUNE SCIENCES INC COM 02083G100 14096 3670955 SH SOLE 3670955 0 0 AMARIN 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