Managing Member

0001172661-15-002104.txt : 20151118 0001172661-15-002104.hdr.sgml : 20151118 20151118160201 ACCESSION NUMBER: 0001172661-15-002104 CONFORMED SUBMISSION TYPE: 13F-HR/A PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20150930 FILED AS OF DATE: 20151118 DATE AS OF CHANGE: 20151118 EFFECTIVENESS DATE: 20151118 FILER: COMPANY DATA: COMPANY CONFORMED NAME: ORBIMED ADVISORS LLC CENTRAL INDEX KEY: 0001055951 IRS NUMBER: 133976876 STATE OF INCORPORATION: DE FILING VALUES: FORM TYPE: 13F-HR/A SEC ACT: 1934 Act SEC FILE NUMBER: 028-06774 FILM NUMBER: 151240729 BUSINESS ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 BUSINESS PHONE: (212) 739-6400 MAIL ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 13F-HR/A 1 primary_doc.xml 13F-HR/A LIVE false true false 0001055951 XXXXXXXX 09-30-2015 09-30-2015 true 1 RESTATEMENT false ORBIMED ADVISORS LLC

601 Lexington Avenue 54th Floor New York NY 10022

13F HOLDINGS REPORT 028-06774 N Samuel D. Isaly Managing Member 212-739-6400 /s/ Samuel D. Isaly New York NY 11-18-2015 1 132 9905986 1 0001157524 028-10410 ORBIMED CAPITAL LLC INFORMATION TABLE 2 infotable.xml ABBOTT LABS COM 002824100 8486 211000 SH DFND 1 53000 0 158000 ABBVIE INC COM 00287Y109 377780 6943200 SH DFND 1 3098500 0 3844700 ACHILLION PHARMACEUTICALS IN COM 00448Q201 36087 5222500 SH DFND 1 2142200 0 3080300 ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 2112 176470 SH SOLE 176470 0 0 ADURO BIOTECH INC COM 00739L101 20639 1065522 SH SOLE 1065522 0 0 ADVAXIS INC COM NEW 007624208 6512 636600 SH DFND 1 0 0 636600 AETNA INC NEW COM 00817Y108 7330 67000 SH DFND 1 18000 0 49000 AFFIMED N V COM N01045108 28275 4582616 SH SOLE 4582616 0 0 AFFYMETRIX INC COM 00826T108 64144 7511000 SH DFND 1 2295000 0 5216000 AGILENT TECHNOLOGIES INC COM 00846U101 121494 3539000 SH DFND 1 1457800 0 2081200 ALEXION PHARMACEUTICALS INC COM 015351109 348218 2226600 SH DFND 1 826400 0 1400200 ALIMERA SCIENCES INC COM 016259103 3315 1500000 SH DFND 1 670000 0 830000 ALIMERA SCIENCES INC 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