144 0001055951 XXXXXXXX LIVE 0001672619 Enliven Therapeutics, Inc. 001-39247 6200 Lookout Road Boulder CO 80301 720-647-8519 OrbiMed Genesis Master Fund, L.P. Shareholder Common Stock Jefferies LLC

520 Madison Ave New York NY 10022

24846 1141922.16 69822989 06/22/2026 Nasdaq Stock Market Common Stock Morgan Stanley & Co. LLC

1585 Broadway New York NY 10036

1477 67882.92 69822989 06/22/2026 Nasdaq Stock Market Common Stock 02/23/2023 Merger Issuer N 26323 02/23/2023 N/A N OrbiMed Genesis Master Fund, L.P.

601 Lexington Ave 54th Floor New York NY 10022

Common Stock 06/15/2026 9086 409051.72 OrbiMed Genesis GP LLC is the general partner of OrbiMed Genesis Master Fund, L.P. OrbiMed Advisors LLC is the managing member of OrbiMed Genesis GP LLC. 06/22/2026 /s/ Douglas Coon, Chief Compliance Officer, OrbiMed Advisors LLC, managing member of the general partner of OrbiMed Genesis Master Fund, L.P.