<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0000947871-25-000546</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: ORBIMED ADVISORS LLC -->
          <cik>0001055951</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>6</amendmentNo>
      <securitiesClassTitle>Common Stock, par value $0.001 per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>06/30/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001528287</issuerCik>
        <issuerName>NeuroPace Inc</issuerName>
        <issuerCusip>641288105</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>455 N. Bernardo Avenue</com:street1>
          <com:city>Mountain View</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94043</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>OrbiMed Advisors LLC</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>2614184.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>2614184.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>2614184.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>8</classPercent>
      <typeOfReportingPerson>IA</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>OrbiMed Capital GP VI LLC</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>2614184.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>2614184.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>2614184.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>8</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>NeuroPace Inc</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>455 N. Bernardo Avenue Mountain View, CA 94043</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>OrbiMed Advisors LLC
OrbiMed Capital GP VI LLC</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>601 Lexington Avenue, 54th Floor  New York, NY 10022</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Please refer to Item 4 on each cover sheet for each filing person.</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
        <typeOfPersonFiling>IA</typeOfPersonFiling>
      </item3>
      <item4>
        <amountBeneficiallyOwned>OrbiMed Advisors LLC: 2,614,184
OrbiMed Capital GP VI LLC: 2,614,184</amountBeneficiallyOwned>
        <classPercent>OrbiMed Advisors LLC: 8.0%
OrbiMed Capital GP VI LLC: 8.0%</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>OrbiMed Advisors LLC: 0
OrbiMed Capital GP VI LLC: 0</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>OrbiMed Advisors LLC: 2,614,184
OrbiMed Capital GP VI LLC: 2,614,184</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>OrbiMed Advisors LLC: 0
OrbiMed Capital GP VI LLC: 0</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>OrbiMed Advisors LLC: 2,614,184
OrbiMed Capital GP VI LLC: 2,614,184</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>N</notApplicableFlag>
        <ownershipMoreThan5PercentOnBehalfOfAnotherPerson>The Reporting Persons hold 8.0% of the shares of Common Stock in the aggregate on behalf of other persons who have the right to receive or the power to direct the receipt of dividends from, or proceeds from the sale of, such securities. OrbiMed Advisors LLC exercises investment and voting power over the shares of Common Stock through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the shares of Common Stock reported herein.</ownershipMoreThan5PercentOnBehalfOfAnotherPerson>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>OrbiMed Advisors LLC</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Carl L. Gordon</signature>
        <title>Carl L. Gordon / Member</title>
        <date>08/14/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>OrbiMed Capital GP VI LLC</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Carl L. Gordon</signature>
        <title>Carl L. Gordon / Member of OrbiMed Advisors LLC</title>
        <date>08/14/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>

</edgarSubmission>
