Authorized Person

0001053906-22-000008.txt : 20220811 0001053906-22-000008.hdr.sgml : 20220811 20220811144532 ACCESSION NUMBER: 0001053906-22-000008 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20220630 FILED AS OF DATE: 20220811 DATE AS OF CHANGE: 20220811 EFFECTIVENESS DATE: 20220811 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Artal Group S.A. CENTRAL INDEX KEY: 0001053906 IRS NUMBER: 000000000 STATE OF INCORPORATION: N4 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-15027 FILM NUMBER: 221155205 BUSINESS ADDRESS: STREET 1: VALLEY PARK STREET 2: 44, RUE DE LA VALLEE CITY: LUXEMBOURG STATE: N4 ZIP: L-2661 BUSINESS PHONE: (352) 22.42.59-1 MAIL ADDRESS: STREET 1: VALLEY PARK STREET 2: 44, RUE DE LA VALLEE CITY: LUXEMBOURG STATE: N4 ZIP: L-2661 FORMER COMPANY: FORMER CONFORMED NAME: ARTAL GROUP S A DATE OF NAME CHANGE: 19980128 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001053906 XXXXXXXX 06-30-2022 06-30-2022 false Artal Group S.A.

VALLEY PARK 44, RUE DE LA VALLEE LUXEMBOURG N4 L-2661

13F HOLDINGS REPORT 028-15027 Y The Reporting Manager does not have formal investment discretion with respect to all of the securities in the indicated rows in the Form 13F Information Table, but may be deemed to be part of a group exercising such investment discretion. Such group, if any, would include the managers identified in the column captioned "Other Managers" relating to a given issuer. The filing of this report shall not be deemed an admission, for purposes of Section 13(f), 13(d), 13(g), or 16(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the rules thereunder, or for any other purpose, that the Reporting Manager or any Other Manager exercises investment discretion or is a member of such a group with respect to such securities. Reference is made to reports filed under Sections 13(d), 13(g), and 16(a) for additional information with respect to such beneficial ownership and/or pecuniary interest of the Reporting Manager, any Other Manager and related entities. Anne Goffard Authorized Person 352224259-1 /s/ Anne Goffard Luxembourg N4 08-11-2022 6 137 1872257 1 0001460840 028-15028 Stichting Administratiekantoor Westend 2 0001283968 028-15029 Westend S.A. 3 0001522131 028-15031 Artal International Management S.A. 4 0001218180 028-15033 Artal International S.C.A. 5 0001340096 028-11522 Invus Public Equities Advisors, LLC 6 0001053905 028-19506 Artal Luxembourg S. A. INFORMATION TABLE 2 infotable.xml 111 INC ADS 68247Q102 1991 966349 SH DFND 1,2,3,4,5,6 966349 0 0 23ANDME HOLDING CO CLASS A COM 90138Q108 1639 661009 SH DFND 1,2,3,4,5,6 661009 0 0 AC IMMUNE SA SHS H00263105 3610 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 5684 2255375 SH DFND 1,2,3,4,5,6 2255375 0 0 ADAGENE INC ADS 005329107 2066 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 ADAGIO THERAPEUTICS INC COM 00534A102 3280 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 ADVERUM BIOTECHNOLOGIES INC COM 00773U108 3600 3000000 SH DFND 1,2,3,4,5,6 3000000 0 0 AGENUS INC COM NEW 00847G705 5820 3000000 SH DFND 1,2,3,4,5,6 3000000 0 0 ALLOVIR INC COM 019818103 9061 2323371 SH DFND 1,2,3,4,5,6 2323371 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 87510 600000 SH DFND 1,2,3,4,5,6 600000 0 0 ALPINE IMMUNE SCIENCES INC COM 02083G100 5047 593030 SH DFND 1,2,3,4,5,6 593030 0 0 ALX ONCOLOGY HLDGS INC COM 00166B105 4045 500000 SH DFND 1,2,3,4,5,6 500000 0 0 AMBRX BIOPHARMA INC SPONSORED ADS 02290A102 5704 2152291 SH DFND 1,2,3,4,5,6 2152291 0 0 AMICUS THERAPEUTICS INC COM 03152W109 42960 4000000 SH DFND 1,2,3,4,5,6 4000000 0 0 AMYLYX PHARMACEUTICALS INC COM 03237H101 1445 75000 SH DFND 1,2,3,4,5,6 75000 0 0 APPLIED THERAPEUTICS INC COM 03828A101 379 400000 SH DFND 1,2,3,4,5,6 400000 0 0 APTINYX INC COM 03836N103 3412 6116493 SH DFND 1,2,3,4,5,6 6116493 0 0 ARAVIVE INC COM 03890D108 1295 1311291 SH DFND 1,2,3,4,5,6 1311291 0 0 ARGENX SE SPONSORED ADR 04016X101 151552 400000 SH DFND 1,2,3,4,5,6 400000 0 0 ASTRIA THERAPEUTICS INC COM 04635X102 100 33333 SH DFND 1,2,3,4,5,6 33333 0 0 ATARA BIOTHERAPEUTICS INC COM 046513107 7790 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 AURINIA PHARMACEUTICALS INC COM 05156V102 10050 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 AVIDITY BIOSCIENCES INC COM 05370A108 3633 250000 SH DFND 1,2,3,4,5,6 250000 0 0 AXCELLA HEALTH INC COM 05454B105 1446 712500 SH DFND 1,2,3,4,5,6 712500 0 0 BATH & BODY WORKS INC COM 070830104 337 12500 SH DFND 1,2,3,4,5,6 12500 0 0 BEIGENE LTD SPONSORED ADR 07725L102 105203 650000 SH DFND 1,2,3,4,5,6 650000 0 0 BELLUS HEALTH INC NEW COM NEW 07987C204 64680 7000000 SH DFND 1,2,3,4,5,6 7000000 0 0 BLACK DIAMOND THERAPEUTICS I COM 09203E105 4050 1646517 SH DFND 1,2,3,4,5,6 1646517 0 0 BRIDGEBIO PHARMA INC COM 10806X102 2270 250000 SH DFND 1,2,3,4,5,6 250000 0 0 CARDIFF ONCOLOGY INC COM 14147L108 1650 750000 SH DFND 1,2,3,4,5,6 750000 0 0 CARIBOU BIOSCIENCES INC COM 142038108 572 105347 SH DFND 1,2,3,4,5,6 105347 0 0 CEREVEL THERAPEUTICS HLDNG I COM 15678U128 39660 1500000 SH DFND 1,2,3,4,5,6 1500000 0 0 CIDARA THERAPEUTICS INC COM 171757107 110 224675 SH DFND 1,2,3,4,5,6 224675 0 0 CINCOR PHARMA INC COM 17240Y109 2581 137010 SH DFND 1,2,3,4,5,6 137010 0 0 CITIGROUP INC COM NEW 172967424 45990 1000000 SH Call DFND 1,2,3,4,5,6 1000000 0 0 CLEVELAND-CLIFFS INC NEW COM 185899101 384 25000 SH DFND 1,2,3,4,5,6 25000 0 0 CODIAK BIOSCIENCES INC COM 192010106 576 200000 SH DFND 1,2,3,4,5,6 200000 0 0 CONTRAFECT CORP COM NEW 212326300 4605 1500000 SH DFND 1,2,3,4,5,6 1500000 0 0 CORVUS PHARMACEUTICALS INC COM 221015100 495 500000 SH DFND 1,2,3,4,5,6 500000 0 0 CULLINAN ONCOLOGY INC COM 230031106 3205 250000 SH DFND 1,2,3,4,5,6 250000 0 0 CURIS INC COM NEW 231269200 1280 1300000 SH DFND 1,2,3,4,5,6 1300000 0 0 CYCLERION THERAPEUTICS INC COM 23255M105 1519 2768069 SH DFND 1,2,3,4,5,6 2768069 0 0 CYCLERION THERAPEUTICS INC COM 23255M105 6 11053 SH DFND 1,2,3,4 11053 0 0 CYTOKINETICS INC COM NEW 23282W605 50095 1275000 SH DFND 1,2,3,4,5,6 1275000 0 0 DENALI THERAPEUTICS INC COM 24823R105 17658 600000 SH DFND 1,2,3,4,5,6 600000 0 0 DESIGN THERAPEUTICS INC COM 25056L103 5600 400000 SH DFND 1,2,3,4,5,6 400000 0 0 DIREXION SHS ETF TR SP BIOTCH BL NEW 25490K323 26960 4000000 SH Call DFND 1,2,3,4,5,6 4000000 0 0 DYNE THERAPEUTICS INC COM 26818M108 3607 525000 SH DFND 1,2,3,4,5,6 525000 0 0 EQRX INC COM 26886C107 18760 4000000 SH DFND 1,2,3,4,5,6 4000000 0 0 ERASCA INC COM 29479A108 17669 3172221 SH DFND 1,2,3,4,5,6 3172221 0 0 EVOTEC AG SPONSORED ADS 30050E105 13770 1149425 SH DFND 1,2,3,4,5,6 1149425 0 0 EXSCIENTIA PLC ADS 30223G102 5990 550000 SH DFND 1,2,3,4,5,6 550000 0 0 FATE THERAPEUTICS INC COM 31189P102 64428 2600000 SH DFND 1,2,3,4,5,6 2600000 0 0 FOGHORN THERAPEUTICS INC COM 344174107 23402 1720720 SH DFND 1,2,3,4,5,6 1720720 0 0 FUSION PHARMACEUTICALS INC COM 36118A100 1868 750000 SH DFND 1,2,3,4,5,6 750000 0 0 GENERATION BIO CO COM 37148K100 18461 2814191 SH DFND 1,2,3,4,5,6 2814191 0 0 GOSSAMER BIO INC COM 38341P102 19745 2358968 SH DFND 1,2,3,4,5,6 2358968 0 0 GRAPHITE BIO INC COM 38870X104 1925 700000 SH DFND 1,2,3,4,5,6 700000 0 0 GRITSTONE BIO INC COM 39868T105 1815 750000 SH DFND 1,2,3,4,5,6 750000 0 0 HARPOON THERAPEUTICS INC COM 41358P106 1910 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 HIPPO HLDGS INC COM 433539103 527 600000 SH DFND 1,2,3,4,5,6 600000 0 0 HOOKIPA PHARMA INC COM 43906K100 3015 1849616 SH DFND 1,2,3,4,5,6 1849616 0 0 IGM BIOSCIENCES INC COM 449585108 36060 2000000 SH DFND 1,2,3,4,5,6 2000000 0 0 IGM BIOSCIENCES INC COM 449585108 902 50000 SH Call DFND 1,2,3,4,5,6 50000 0 0 IKENA ONCOLOGY INC COM 45175G108 6864 1549513 SH DFND 1,2,3,4,5,6 1549513 0 0 I MAB SPONSORED ADS 44975P103 9605 850000 SH DFND 1,2,3,4,5,6 850000 0 0 IMMUNIC INC COM 4525EP101 2429 700000 SH DFND 1,2,3,4,5,6 700000 0 0 IMMUTEP LTD SPONSORED ADS 45257L108 2030 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 INSTIL BIO INC COM 45783C101 2079 450000 SH DFND 1,2,3,4,5,6 450000 0 0 INTELLIA THERAPEUTICS INC COM 45826J105 14234 275000 SH DFND 1,2,3,4,5,6 275000 0 0 IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 1274 110532 SH DFND 1,2,3,4 110532 0 0 ITEOS THERAPEUTICS INC COM 46565G104 8240 400000 SH DFND 1,2,3,4,5,6 400000 0 0 KALEIDO BIOSCIENCES INC COM 483347100 31 500500 SH DFND 1,2,3,4,5,6 500500 0 0 KINNATE BIOPHARMA INC COM 49705R105 1576 125000 SH DFND 1,2,3,4,5,6 125000 0 0 KRONOS BIO INC COM 50107A104 5616 1542954 SH DFND 1,2,3,4,5,6 1542954 0 0 KRYSTAL BIOTECH INC COM 501147102 32830 500000 SH DFND 1,2,3,4,5,6 500000 0 0 KURA ONCOLOGY INC COM 50127T109 19247 1050000 SH DFND 1,2,3,4,5,6 1050000 0 0 KYMERA THERAPEUTICS INC COM 501575104 19690 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 LAVA THERAPEUTICS NV SHS N51517105 590 200000 SH DFND 1,2,3,4,5,6 200000 0 0 LEAP THERAPEUTICS INC COM 52187K101 4600 4000000 SH DFND 1,2,3,4,5,6 4000000 0 0 LEXICON PHARMACEUTICALS INC COM NEW 528872302 6540 3516214 SH DFND 1,2,3,4,5,6 3516214 0 0 LEXICON PHARMACEUTICALS INC COM NEW 528872302 125852 67662150 SH DFND 1,2,3,4 67662150 0 0 LYELL IMMUNOPHARMA INC COM 55083R104 4564 700000 SH DFND 1,2,3,4,5,6 700000 0 0 MARINUS PHARMACEUTICALS INC COM NEW 56854Q200 4840 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 MEI PHARMA INC COM NEW 55279B202 605 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 MEREO BIOPHARMA GROUP PLC ADS 589492107 1680 1500000 SH DFND 1,2,3,4,5,6 1500000 0 0 MERSANA THERAPEUTICS INC COM 59045L106 10164 2200000 SH DFND 1,2,3,4,5,6 2200000 0 0 METACRINE INC COM 59101E103 462 924898 SH DFND 1,2,3,4,5,6 924898 0 0 MINK THERAPEUTICS INC COM 603693102 408 289588 SH DFND 1,2,3,4,5,6 289588 0 0 MIRATI THERAPEUTICS INC COM 60468T105 73843 1100000 SH DFND 1,2,3,4,5,6 1100000 0 0 MIRION TECHNOLOGIES INC COM CL A 60471A101 2880 500000 SH DFND 1,2,3,4,5,6 500000 0 0 MORPHIC HLDG INC COM 61775R105 35805 1650000 SH DFND 1,2,3,4,5,6 1650000 0 0 NANOBIOTIX SPONSORED ADS 63009J107 3800 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 NEXIMMUNE INC COM 65344D109 1932 1200000 SH DFND 1,2,3,4,5,6 1200000 0 0 OATLY GROUP AB SPONSORED ADS 67421J108 5190 1500000 SH DFND 1,2,3,4,5,6 1500000 0 0 OLEMA PHARMACEUTICALS INC COM 68062P106 1060 260500 SH DFND 1,2,3,4,5,6 260500 0 0 OMEGA ALPHA SPAC CL A G6749V107 7388 750000 SH DFND 1,2,3,4,5,6 750000 0 0 OMEGA THERAPEUTICS INC COM 68217N105 8639 2273530 SH DFND 1,2,3,4,5,6 2273530 0 0 ORCHARD THERAPEUTICS PLC ADS 68570P101 1054 1803858 SH DFND 1,2,3,4,5,6 1803858 0 0 ORIC PHARMACEUTICALS INC COM 68622P109 1792 400000 SH DFND 1,2,3,4,5,6 400000 0 0 OVID THERAPEUTICS INC COM 690469101 5375 2500000 SH DFND 1,2,3,4,5,6 2500000 0 0 PORTAGE FINTECH ACQUISITN CO CLASS A ORD SHS G7185D106 3705 380000 SH DFND 1,2,3,4,5,6 380000 0 0 PRAXIS PRECISION MEDICINES I COM 74006W108 2940 1200000 SH DFND 1,2,3,4,5,6 1200000 0 0 RECURSION PHARMACEUTICALS IN CL A 75629V104 3663 450000 SH DFND 1,2,3,4,5,6 450000 0 0 RELAY THERAPEUTICS INC COM 75943R102 11725 700000 SH DFND 1,2,3,4,5,6 700000 0 0 REPARE THERAPEUTICS INC COM 760273102 9793 700000 SH DFND 1,2,3,4,5,6 700000 0 0 REPLIMUNE GROUP INC COM 76029N106 15732 900000 SH DFND 1,2,3,4,5,6 900000 0 0 RUBIUS THERAPEUTICS INC COM 78116T103 3149 3701580 SH DFND 1,2,3,4,5,6 3701580 0 0 SAGE THERAPEUTICS INC COM 78667J108 14535 450000 SH DFND 1,2,3,4,5,6 450000 0 0 SANA BIOTECHNOLOGY INC COM 799566104 2572 400000 SH DFND 1,2,3,4,5,6 400000 0 0 SCHOLAR ROCK HLDG CORP COM 80706P103 48038 8750034 SH DFND 1,2,3,4,5,6 8750034 0 0 SCHRODINGER INC COM 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