Authorized Person

0001053906-22-000005.txt : 20220512 0001053906-22-000005.hdr.sgml : 20220512 20220512110625 ACCESSION NUMBER: 0001053906-22-000005 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20220331 FILED AS OF DATE: 20220512 DATE AS OF CHANGE: 20220512 EFFECTIVENESS DATE: 20220512 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Artal Group S.A. CENTRAL INDEX KEY: 0001053906 IRS NUMBER: 000000000 STATE OF INCORPORATION: N4 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-15027 FILM NUMBER: 22916428 BUSINESS ADDRESS: STREET 1: VALLEY PARK STREET 2: 44, RUE DE LA VALLEE CITY: LUXEMBOURG STATE: N4 ZIP: L-2661 BUSINESS PHONE: (352) 22.42.59-1 MAIL ADDRESS: STREET 1: VALLEY PARK STREET 2: 44, RUE DE LA VALLEE CITY: LUXEMBOURG STATE: N4 ZIP: L-2661 FORMER COMPANY: FORMER CONFORMED NAME: ARTAL GROUP S A DATE OF NAME CHANGE: 19980128 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001053906 XXXXXXXX 03-31-2022 03-31-2022 false Artal Group S.A.

VALLEY PARK 44, RUE DE LA VALLEE LUXEMBOURG N4 L-2661

13F HOLDINGS REPORT 028-15027 Y The Reporting Manager does not have formal investment discretion with respect to all of the securities in the indicated rows in the Form 13F Information Table, but may be deemed to be part of a group exercising such investment discretion. Such group, if any, would include the managers identified in the column captioned "Other Managers" relating to a given issuer. The filing of this report shall not be deemed an admission, for purposes of Section 13(f), 13(d), 13(g), or 16(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the rules thereunder, or for any other purpose, that the Reporting Manager or any Other Manager exercises investment discretion or is a member of such a group with respect to such securities. Reference is made to reports filed under Sections 13(d), 13(g), and 16(a) for additional information with respect to such beneficial ownership and/or pecuniary interest of the Reporting Manager, any Other Manager and related entities. Anne Goffard Authorized Person 352224259-1 /s/ Anne Goffard Luxembourg N4 05-09-2022 6 139 2388477 1 0001460840 028-15028 Stichting Administratiekantoor Westend 2 0001283968 028-15029 Westend S.A. 3 0001522131 028-15031 Artal International Management S.A. 4 0001218180 028-15033 Artal International S.C.A. 5 0001340096 028-11522 Invus Public Equities Advisors, LLC 6 0001053905 028-19506 Artal Luxembourg S. A. INFORMATION TABLE 2 infotable.xml 111 INC ADS 68247Q102 2570 966349 SH DFND 1,2,3,4,5 966349 0 0 23ANDME HOLDING CO CLASS A COM 90138Q108 2532 661009 SH DFND 1,2,3,4,5 661009 0 0 AC IMMUNE SA SHS H00263105 4000 1000000 SH DFND 1,2,3,4,5 1000000 0 0 ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 6631 2255375 SH DFND 1,2,3,4,5 2255375 0 0 ADAGENE INC ADS 005329107 3500 1000000 SH DFND 1,2,3,4,5 1000000 0 0 ADAGIO THERAPEUTICS INC COM 00534A102 4560 1000000 SH DFND 1,2,3,4,5 1000000 0 0 ADVERUM BIOTECHNOLOGIES INC COM 00773U108 3930 3000000 SH DFND 1,2,3,4,5 3000000 0 0 AGENUS INC COM NEW 00847G705 13530 5500000 SH DFND 1,2,3,4,5 5500000 0 0 ALLOVIR INC COM 019818103 15683 2323371 SH DFND 1,2,3,4,5 2323371 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 106139 650000 SH DFND 1,2,3,4,5 650000 0 0 ALPINE IMMUNE SCIENCES INC COM 02083G100 5319 593030 SH DFND 1,2,3,4,5 593030 0 0 ALX ONCOLOGY HLDGS INC COM 00166B105 8450 500000 SH DFND 1,2,3,4,5 500000 0 0 AMBRX BIOPHARMA INC SPONSORED ADS 02290A102 8867 2152291 SH DFND 1,2,3,4,5 2152291 0 0 AMICUS THERAPEUTICS INC COM 03152W109 37880 4000000 SH DFND 1,2,3,4,5 4000000 0 0 AMYLYX PHARMACEUTICALS INC COM 03237H101 964 75000 SH DFND 1,2,3,4,5 75000 0 0 APELLIS PHARMACEUTICALS INC COM 03753U106 10162 200000 SH DFND 1,2,3,4,5 200000 0 0 APPLIED THERAPEUTICS INC COM 03828A101 844 400000 SH DFND 1,2,3,4,5 400000 0 0 APTINYX INC COM 03836N103 13884 6116493 SH DFND 1,2,3,4,5 6116493 0 0 ARAVIVE INC COM 03890D108 2531 1311291 SH DFND 1,2,3,4,5 1311291 0 0 ARGENX SE SPONSORED ADR 04016X101 185245 587500 SH DFND 1,2,3,4,5 587500 0 0 ASTRIA THERAPEUTICS INC COM 04635X102 224 33333 SH DFND 1,2,3,4,5 33333 0 0 ATARA BIOTHERAPEUTICS INC COM 046513107 9290 1000000 SH DFND 1,2,3,4,5 1000000 0 0 AURINIA PHARMACEUTICALS INC COM 05156V102 12380 1000000 SH DFND 1,2,3,4,5 1000000 0 0 AVIDITY BIOSCIENCES INC COM 05370A108 4618 250000 SH DFND 1,2,3,4,5 250000 0 0 AXCELLA HEALTH INC COM 05454B105 1831 712500 SH DFND 1,2,3,4,5 712500 0 0 BEIGENE LTD SPONSORED ADR 07725L102 125419 665000 SH DFND 1,2,3,4,5 665000 0 0 BELLUS HEALTH INC NEW COM NEW 07987C204 58480 8500000 SH DFND 1,2,3,4,5 8500000 0 0 BLACK DIAMOND THERAPEUTICS I COM 09203E105 4561 1646517 SH DFND 1,2,3,4,5 1646517 0 0 BRIDGEBIO PHARMA INC COM 10806X102 2538 250000 SH DFND 1,2,3,4,5 250000 0 0 CARDIFF ONCOLOGY INC COM 14147L108 1860 750000 SH DFND 1,2,3,4,5 750000 0 0 CARIBOU BIOSCIENCES INC COM 142038108 967 105347 SH DFND 1,2,3,4,5 105347 0 0 CEREVEL THERAPEUTICS HLDNG I COM 15678U128 52515 1500000 SH DFND 1,2,3,4,5 1500000 0 0 CIDARA THERAPEUTICS INC COM 171757107 187 224675 SH DFND 1,2,3,4,5 224675 0 0 CODIAK BIOSCIENCES INC COM 192010106 1254 200000 SH DFND 1,2,3,4,5 200000 0 0 CONTRAFECT CORP COM NEW 212326300 5475 1500000 SH DFND 1,2,3,4,5 1500000 0 0 CORVUS PHARMACEUTICALS INC COM 221015100 820 500000 SH DFND 1,2,3,4,5 500000 0 0 CULLINAN ONCOLOGY INC COM 230031106 2618 250000 SH DFND 1,2,3,4,5 250000 0 0 CURIS INC COM NEW 231269200 3094 1300000 SH DFND 1,2,3,4,5 1300000 0 0 CYCLERION THERAPEUTICS INC COM 23255M105 3073 2768069 SH DFND 1,2,3,4,5 2768069 0 0 CYCLERION THERAPEUTICS INC COM 23255M105 12 11053 SH DFND 1,2,3,4 11053 0 0 CYTOKINETICS INC COM NEW 23282W605 36810 1000000 SH DFND 1,2,3,4,5 1000000 0 0 DENALI THERAPEUTICS INC COM 24823R105 19302 600000 SH DFND 1,2,3,4,5 600000 0 0 DESIGN THERAPEUTICS INC COM 25056L103 6460 400000 SH DFND 1,2,3,4,5 400000 0 0 DYNAMICS SPECIAL PURPOSE COR CLASS A COM 268010105 4935 500000 SH DFND 1,2,3,4,5 500000 0 0 DYNE THERAPEUTICS INC COM 26818M108 5061 525000 SH DFND 1,2,3,4,5 525000 0 0 EQRX INC COM 26886C107 16520 4000000 SH DFND 1,2,3,4,5 4000000 0 0 ERASCA INC COM 29479A108 27281 3172221 SH DFND 1,2,3,4,5 3172221 0 0 EVOTEC AG SPONSORED ADS 30050E105 17391 1149425 SH DFND 1,2,3,4,5 1149425 0 0 EXSCIENTIA PLC ADS 30223G102 7920 550000 SH DFND 1,2,3,4,5 550000 0 0 FATE THERAPEUTICS INC COM 31189P102 77540 2000000 SH DFND 1,2,3,4,5 2000000 0 0 FOGHORN THERAPEUTICS INC COM 344174107 26207 1720720 SH DFND 1,2,3,4,5 1720720 0 0 FORMA THERAPEUTICS HLDGS INC SHS 34633R104 9300 1000000 SH DFND 1,2,3,4,5 1000000 0 0 FUSION PHARMACEUTICALS INC COM 36118A100 5828 750000 SH DFND 1,2,3,4,5 750000 0 0 GENERATION BIO CO COM 37148K100 20656 2814191 SH DFND 1,2,3,4,5 2814191 0 0 GINKGO BIOWORKS HOLDINGS INC CL A SHS 37611X100 202 50000 SH DFND 1,2,3,4,5 50000 0 0 GOSSAMER BIO INC COM 38341P102 20476 2358968 SH DFND 1,2,3,4,5 2358968 0 0 GRAPHITE BIO INC COM 38870X104 3570 700000 SH DFND 1,2,3,4,5 700000 0 0 GRITSTONE BIO INC COM 39868T105 3090 750000 SH DFND 1,2,3,4,5 750000 0 0 HARPOON THERAPEUTICS INC COM 41358P106 4970 1000000 SH DFND 1,2,3,4,5 1000000 0 0 HIPPO HLDGS INC COMMON STOCK 433539103 1194 600000 SH DFND 1,2,3,4,5 600000 0 0 HOOKIPA PHARMA INC COM 43906K100 4217 1849616 SH DFND 1,2,3,4,5 1849616 0 0 IGM BIOSCIENCES INC COM 449585108 53460 2000000 SH DFND 1,2,3,4,5 2000000 0 0 IKENA ONCOLOGY INC COM 45175G108 9452 1549513 SH DFND 1,2,3,4,5 1549513 0 0 I MAB SPONSORED ADS 44975P103 13804 850000 SH DFND 1,2,3,4,5 850000 0 0 IMMUNIC INC COM 4525EP101 7910 700000 SH DFND 1,2,3,4,5 700000 0 0 IMMUNOCORE HLDGS PLC ADS 45258D105 5980 200000 SH DFND 1,2,3,4,5 200000 0 0 IMMUTEP LTD SPONSORED ADS 45257L108 2740 1000000 SH DFND 1,2,3,4,5 1000000 0 0 INSTIL BIO INC COM 45783C101 4838 450000 SH DFND 1,2,3,4,5 450000 0 0 INTEL CORP COM 458140100 14856 300000 SH Call DFND 1,2,3,4,5 300000 0 0 INTELLIA THERAPEUTICS INC COM 45826J105 19984 275000 SH DFND 1,2,3,4,5 275000 0 0 IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 1390 110532 SH DFND 1,2,3,4 110532 0 0 ITEOS THERAPEUTICS INC COM 46565G104 12872 400000 SH DFND 1,2,3,4,5 400000 0 0 KALEIDO BIOSCIENCES INC COM 483347100 826 500500 SH DFND 1,2,3,4,5 500500 0 0 KINNATE BIOPHARMA INC COM 49705R105 1408 125000 SH DFND 1,2,3,4,5 125000 0 0 KRONOS BIO INC COM 50107A104 11156 1542954 SH DFND 1,2,3,4,5 1542954 0 0 KRYSTAL BIOTECH INC COM 501147102 33270 500000 SH DFND 1,2,3,4,5 500000 0 0 KURA ONCOLOGY INC COM 50127T109 16884 1050000 SH DFND 1,2,3,4,5 1050000 0 0 KYMERA THERAPEUTICS INC COM 501575104 42320 1000000 SH DFND 1,2,3,4,5 1000000 0 0 LAVA THERAPEUTICS NV SHS N51517105 880 200000 SH DFND 1,2,3,4,5 200000 0 0 LEAP THERAPEUTICS INC COM 52187K101 7000 4000000 SH DFND 1,2,3,4,5 4000000 0 0 LEXICON PHARMACEUTICALS INC COM NEW 528872302 7349 3516214 SH DFND 1,2,3,4,5 3516214 0 0 LEXICON PHARMACEUTICALS INC COM NEW 528872302 141414 67662150 SH DFND 1,2,3,4 67662150 0 0 LYELL IMMUNOPHARMA INC COM 55083R104 3535 700000 SH DFND 1,2,3,4,5 700000 0 0 MARINUS PHARMACEUTICALS INC COM NEW 56854Q200 9350 1000000 SH DFND 1,2,3,4,5 1000000 0 0 MEI PHARMA INC COM NEW 55279B202 603 1000000 SH DFND 1,2,3,4,5 1000000 0 0 MEREO BIOPHARMA GROUP PLC ADS 589492107 1680 1500000 SH DFND 1,2,3,4,5 1500000 0 0 MERSANA THERAPEUTICS INC COM 59045L106 8778 2200000 SH DFND 1,2,3,4,5 2200000 0 0 METACRINE INC COM 59101E103 564 924898 SH DFND 1,2,3,4,5 924898 0 0 MINK THERAPEUTICS INC COM 603693102 652 289588 SH DFND 1,2,3,4,5 289588 0 0 MIRATI THERAPEUTICS INC COM 60468T105 110997 1350000 SH DFND 1,2,3,4,5 1350000 0 0 MIRION TECHNOLOGIES INC COM CL A 60471A101 4035 500000 SH DFND 1,2,3,4,5 500000 0 0 MORPHIC HLDG INC COM 61775R105 66248 1650000 SH DFND 1,2,3,4,5 1650000 0 0 NANOBIOTIX SA SPONSORED ADS 63009J107 7440 1000000 SH DFND 1,2,3,4,5 1000000 0 0 NEXIMMUNE INC COM 65344D109 5052 1200000 SH DFND 1,2,3,4,5 1200000 0 0 OATLY GROUP AB SPONSORED ADS 67421J108 7515 1500000 SH DFND 1,2,3,4,5 1500000 0 0 OLEMA PHARMACEUTICALS INC COM 68062P106 1110 260500 SH DFND 1,2,3,4,5 260500 0 0 OMEGA ALPHA SPAC CL A G6749V107 7365 750000 SH DFND 1,2,3,4,5 750000 0 0 OMEGA THERAPEUTICS INC COMMON STOCK 68217N105 14187 2273530 SH DFND 1,2,3,4,5 2273530 0 0 ORCHARD THERAPEUTICS PLC ADS 68570P101 1284 1803858 SH DFND 1,2,3,4,5 1803858 0 0 ORIC PHARMACEUTICALS INC COM 68622P109 2136 400000 SH DFND 1,2,3,4,5 400000 0 0 OVID THERAPEUTICS INC COM 690469101 7850 2500000 SH DFND 1,2,3,4,5 2500000 0 0 PORTAGE FINTECH ACQUISITN CO CLASS A ORD SHS G7185D106 3773 380000 SH DFND 1,2,3,4,5 380000 0 0 PRAXIS PRECISION MEDICINES I COM 74006W108 12252 1200000 SH DFND 1,2,3,4,5 1200000 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 18946 800100 SH DFND 1,2,3,4,5 800100 0 0 RECURSION PHARMACEUTICALS IN CL A 75629V104 3222 450000 SH DFND 1,2,3,4,5 450000 0 0 RELAY THERAPEUTICS INC COM 75943R102 20951 700000 SH DFND 1,2,3,4,5 700000 0 0 REPARE THERAPEUTICS INC COM 760273102 9968 700000 SH DFND 1,2,3,4,5 700000 0 0 REPLIMUNE GROUP INC COM 76029N106 15282 900000 SH DFND 1,2,3,4,5 900000 0 0 RUBIUS THERAPEUTICS INC COM 78116T103 20396 3701580 SH DFND 1,2,3,4,5 3701580 0 0 SAGE THERAPEUTICS INC COM 78667J108 24825 750000 SH DFND 1,2,3,4,5 750000 0 0 SAGE THERAPEUTICS INC COM 78667J108 8275 250000 SH Call DFND 1,2,3,4,5 250000 0 0 SANA BIOTECHNOLOGY INC COM 799566104 3304 400000 SH DFND 1,2,3,4,5 400000 0 0 SCHOLAR ROCK HLDG CORP COM 80706P103 31581 2450000 SH DFND 1,2,3,4,5 2450000 0 0 SCHRODINGER INC COM 80810D103 23884 700000 SH DFND 1,2,3,4,5 700000 0 0 SEA LTD SPONSORED ADS 81141R100 6888 57500 SH DFND 1,2,3,4,5 57500 0 0 SEAGEN INC COM 81181C104 93633 650000 SH DFND 1,2,3,4,5 650000 0 0 SEER INC COM CL A 81578P106 72390 4750000 SH DFND 1,2,3,4,5 4750000 0 0 SELECTA BIOSCIENCES INC COM 816212104 4920 4000000 SH DFND 1,2,3,4,5 4000000 0 0 SIGILON THERAPEUTICS INC COM 82657L107 406 276000 SH DFND 1,2,3,4,5 276000 0 0 SOLID BIOSCIENCES INC COM 83422E105 3600 3000000 SH DFND 1,2,3,4,5 3000000 0 0 SPERO THERAPEUTICS INC COM 84833T103 4350 500000 SH DFND 1,2,3,4,5 500000 0 0 SPRINGWORKS THERAPEUTICS INC COM 85205L107 47974 850000 SH DFND 1,2,3,4,5 850000 0 0 SQZ BIOTECHNOLOGIES CO COM 78472W104 7726 1606309 SH DFND 1,2,3,4,5 1606309 0 0 STOKE THERAPEUTICS INC COM 86150R107 5263 250000 SH DFND 1,2,3,4,5 250000 0 0 SYROS PHARMACEUTICALS INC COM 87184Q107 4165 3500000 SH DFND 1,2,3,4,5 3500000 0 0 TALARIS THERAPEUTICS INC COM 87410C104 20312 2064262 SH DFND 1,2,3,4,5 2064262 0 0 TAYSHA GENE THERAPIES INC COM SHS 877619106 6787 1040882 SH DFND 1,2,3,4,5 1040882 0 0 TCR2 THERAPEUTICS INC COM 87808K106 2070 750000 SH DFND 1,2,3,4,5 750000 0 0 TG THERAPEUTICS INC COM 88322Q108 7608 800000 SH DFND 1,2,3,4,5 800000 0 0 VERVE THERAPEUTICS INC COM 92539P101 9128 400000 SH DFND 1,2,3,4,5 400000 0 0 VIGIL NEUROSCIENCE INC COM 92673K108 7882 1121191 SH DFND 1,2,3,4,5 1121191 0 0 VOR BIOPHARMA INC COM 929033108 3322 550000 SH DFND 1,2,3,4,5 550000 0 0 WAVE LIFE SCIENCES LTD SHS Y95308105 2000 1000000 SH DFND 1,2,3,4,5 1000000 0 0 WW INTL INC COM 98262P101 151591 14818300 SH DFND 1,2,3,4,6 14818300 0 0 XILIO THERAPEUTICS INC COM 98422T100 3182 450000 SH DFND 1,2,3,4,5 450000 0 0 XP INC CL A G98239109 1054 35000 SH DFND 1,2,3,4,5 35000 0 0 Y-MABS THERAPEUTICS INC COM 984241109 4752 400000 SH DFND 1,2,3,4,5 400000 0 0 YUMANITY THERAPEUTICS INC COM 98872L102 326 217391 SH DFND 1,2,3,4,5 217391 0 0 ZYMEWORKS INC COM 98985W102 2948 450000 SH DFND 1,2,3,4,5 450000 0 0