Authorized Person

0001053906-21-000007.txt : 20210813 0001053906-21-000007.hdr.sgml : 20210813 20210813133549 ACCESSION NUMBER: 0001053906-21-000007 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20210630 FILED AS OF DATE: 20210813 DATE AS OF CHANGE: 20210813 EFFECTIVENESS DATE: 20210813 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Artal Group S.A. CENTRAL INDEX KEY: 0001053906 IRS NUMBER: 000000000 STATE OF INCORPORATION: N4 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-15027 FILM NUMBER: 211171235 BUSINESS ADDRESS: STREET 1: VALLEY PARK STREET 2: 44, RUE DE LA VALLEE CITY: LUXEMBOURG STATE: N4 ZIP: L-2661 BUSINESS PHONE: (352) 22.42.59-1 MAIL ADDRESS: STREET 1: VALLEY PARK STREET 2: 44, RUE DE LA VALLEE CITY: LUXEMBOURG STATE: N4 ZIP: L-2661 FORMER COMPANY: FORMER CONFORMED NAME: ARTAL GROUP S A DATE OF NAME CHANGE: 19980128 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001053906 XXXXXXXX 06-30-2021 06-30-2021 false Artal Group S.A.

VALLEY PARK 44, RUE DE LA VALLEE LUXEMBOURG N4 L-2661

13F HOLDINGS REPORT 028-15027 Y The Reporting Manager does not have formal investment discretion with respect to all of the securities in the indicated rows in the Form 13F Information Table, but may be deemed to be part of a group exercising such investment discretion. Such group, if any, would include the managers identified in the column captioned "Other Managers" relating to a given issuer. The filing of this report shall not be deemed an admission, for purposes of Section 13(f), 13(d), 13(g), or 16(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the rules thereunder, or for any other purpose, that the Reporting Manager or any Other Manager exercises investment discretion or is a member of such a group with respect to such securities. Reference is made to reports filed under Sections 13(d), 13(g), and 16(a) for additional information with respect to such beneficial ownership and/or pecuniary interest of the Reporting Manager, any Other Manager and related entities. Anne Goffard Authorized Person 352224259-1 /s/ Anne Goffard Luxembourg N4 08-13-2021 7 146 4927049 1 0001460840 028-15028 Stichting Administratiekantoor Westend 2 0001283968 028-15029 Westend S.A. 3 0001522131 028-15031 Artal International Management S.A. 4 0001218180 028-15033 Artal International S.C.A. 5 0001766952 028-19088 Artal Treasury Ltd 6 0001340096 028-11522 Invus Public Equities Advisors, LLC 7 0001053905 028-19506 Artal Luxembourg S. A. INFORMATION TABLE 2 infotable.xml 111 INC ADS 68247Q102 8779 966349 SH DFND 1,2,3,4,5,6 966349 0 0 AC IMMUNE SA SHS H00263105 7930 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 ACCELERON PHARMA INC COM 00434H108 175686 1400000 SH DFND 1,2,3,4,5,6 1400000 0 0 ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 22080 2255375 SH DFND 1,2,3,4,5,6 2255375 0 0 ADAGENE INC ADS 005329107 13560 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 ADVERUM BIOTECHNOLOGIES INC COM 00773U108 10500 3000000 SH DFND 1,2,3,4,5,6 3000000 0 0 AEGLEA BIOTHERAPEUTICS INC COM 00773J103 7273 1045000 SH DFND 1,2,3,4,5,6 1045000 0 0 AGENUS INC COM NEW 00847G705 32940 6000000 SH DFND 1,2,3,4,5,6 6000000 0 0 AGILON HEALTH INC COM 00857U107 12171 300000 SH DFND 1,2,3,4,5,6 300000 0 0 ALBIREO PHARMA INC COM 01345P106 21108 600000 SH DFND 1,2,3,4,5,6 600000 0 0 ALDEYRA THERAPEUTICS INC COM 01438T106 4893 431894 SH DFND 1,2,3,4,5,6 431894 0 0 ALLOVIR INC COM 019818103 45863 2323371 SH DFND 1,2,3,4,5,6 2323371 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 127140 750000 SH DFND 1,2,3,4,5,6 750000 0 0 ALPINE IMMUNE SCIENCES INC COM 02083G100 5337 593030 SH DFND 1,2,3,4,5,6 593030 0 0 ALX ONCOLOGY HLDGS INC COM 00166B105 27340 500000 SH DFND 1,2,3,4,5,6 500000 0 0 AMBRX BIOPHARMA INC SPONSORED ADS 02290A102 16660 850000 SH DFND 1,2,3,4,5,6 850000 0 0 AMICUS THERAPEUTICS INC COM 03152W109 36150 3750000 SH DFND 1,2,3,4,5,6 3750000 0 0 APPLIED THERAPEUTICS INC COM 03828A101 8312 400000 SH DFND 1,2,3,4,5,6 400000 0 0 APTINYX INC COM 03836N103 17310 6116493 SH DFND 1,2,3,4,5,6 6116493 0 0 ARAVIVE INC COM 03890D108 7842 1311291 SH DFND 1,2,3,4,5,6 1311291 0 0 ARGENX SE SPONSORED ADR 04016X101 150535 500000 SH DFND 1,2,3,4,5,6 500000 0 0 ATARA BIOTHERAPEUTICS INC COM 046513107 23325 1500000 SH DFND 1,2,3,4,5,6 1500000 0 0 AURINIA PHARMACEUTICALS INC COM 05156V102 12960 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 AVIDITY BIOSCIENCES INC COM 05370A108 3521 142500 SH DFND 1,2,3,4,5,6 142500 0 0 AVIS BUDGET GROUP COM 053774105 23367 300000 SH DFND 1,2,3,4,5,6 300000 0 0 AXCELLA HEALTH INC COM 05454B105 2857 712500 SH DFND 1,2,3,4,5,6 712500 0 0 BEIGENE LTD SPONSORED ADR 07725L102 291712 850000 SH DFND 1,2,3,4,5,6 850000 0 0 BELLUS HEALTH INC NEW COM NEW 07987C204 14773 4750000 SH DFND 1,2,3,4,5,6 4750000 0 0 BIOHAVEN PHARMACTL HLDG CO L COM G11196105 38832 400000 SH DFND 1,2,3,4,5,6 400000 0 0 BLACK DIAMOND THERAPEUTICS I COM 09203E105 20071 1646517 SH DFND 1,2,3,4,5,6 1646517 0 0 BLUEPRINT MEDICINES CORP COM 09627Y109 8796 100000 SH DFND 1,2,3,4,5,6 100000 0 0 BRIDGEBIO PHARMA INC COM 10806X102 16764 275000 SH DFND 1,2,3,4,5,6 275000 0 0 BRIGHT HEALTH GROUP INC COM 10920V107 5243 305555 SH DFND 1,2,3,4,5,6 305555 0 0 BRISTOL-MYERS SQUIBB CO COM 110122108 66820 1000000 SH Call DFND 1,2,3,4,5,6 1000000 0 0 CARDIFF ONCOLOGY INC COM 14147L108 4988 750000 SH DFND 1,2,3,4,5,6 750000 0 0 CEREVEL THERAPEUTICS HLDNG I *W EXP 06/09/202 15678U102 1145 79600 SH DFND 1,2,3,4,5,6 79600 0 0 CEREVEL THERAPEUTICS HLDNG I COM 15678U128 51240 2000000 SH DFND 1,2,3,4,5,6 2000000 0 0 CHIASMA INC COM 16706W102 1797 380000 SH DFND 1,2,3,4,5,6 380000 0 0 CHINOOK THERAPEUTICS INC COM 16961L106 2549 180500 SH DFND 1,2,3,4,5,6 180500 0 0 CIDARA THERAPEUTICS INC COM 171757107 454 224675 SH DFND 1,2,3,4,5,6 224675 0 0 CITIGROUP INC COM NEW 172967424 194563 2750000 SH Call DFND 1,2,3,4,5,6 2750000 0 0 CODIAK BIOSCIENCES INC COM 192010106 3706 200000 SH DFND 1,2,3,4,5,6 200000 0 0 CONTRAFECT CORP COM NEW 212326300 6600 1500000 SH DFND 1,2,3,4,5,6 1500000 0 0 CULLINAN ONCOLOGY INC COM 230031106 2575 100000 SH DFND 1,2,3,4,5,6 100000 0 0 CURIS INC COM NEW 231269200 10491 1300000 SH DFND 1,2,3,4,5,6 1300000 0 0 CYCLERION THERAPEUTICS INC COM 23255M105 10795 2768069 SH DFND 1,2,3,4,5,6 2768069 0 0 CYCLERION THERAPEUTICS INC COM 23255M105 43 11053 SH DFND 1,2,3,4 11053 0 0 CYTOKINETICS INC COM NEW 23282W605 9895 500000 SH DFND 1,2,3,4,5,6 500000 0 0 DECIPHERA PHARMACEUTICALS IN COM 24344T101 7322 200000 SH DFND 1,2,3,4,5,6 200000 0 0 DENALI THERAPEUTICS INC COM 24823R105 39220 500000 SH DFND 1,2,3,4,5,6 500000 0 0 DESIGN THERAPEUTICS INC COM 25056L103 7956 400000 SH DFND 1,2,3,4,5,6 400000 0 0 DICERNA PHARMACEUTICALS INC COM 253031108 29856 800000 SH DFND 1,2,3,4,5,6 800000 0 0 DLOCAL LTD CLASS A COM G29018101 15496 295000 SH DFND 1,2,3,4,5,6 295000 0 0 DYNAMICS SPECIAL PURPOSE COR CLASS A COM 268010105 4970 500000 SH DFND 1,2,3,4,5,6 500000 0 0 DYNE THERAPEUTICS INC COM 26818M108 11046 525000 SH DFND 1,2,3,4,5,6 525000 0 0 EVELO BIOSCIENCES INC COM 299734103 13740 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 FATE THERAPEUTICS INC COM 31189P102 117167 1350000 SH DFND 1,2,3,4,5,6 1350000 0 0 FOGHORN THERAPEUTICS INC COM 344174107 18360 1720720 SH DFND 1,2,3,4,5,6 1720720 0 0 FORD MTR CO DEL COM 345370860 52010 3500000 SH Call DFND 1,2,3,4,5,6 3500000 0 0 FORMA THERAPEUTICS HLDGS INC SHS 34633R104 24890 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 FREEPORT-MCMORAN INC CL B 35671D857 27833 750000 SH Call DFND 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1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 INSTIL BIO INC COM 45783C101 8694 450000 SH DFND 1,2,3,4,5,6 450000 0 0 INTEL CORP COM 458140100 72982 1300000 SH Call DFND 1,2,3,4,5,6 1300000 0 0 INTELLIA THERAPEUTICS INC COM 45826J105 40478 250000 SH DFND 1,2,3,4,5,6 250000 0 0 IQIYI INC SPONSORED ADS 46267X108 15580 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 1423 110532 SH DFND 1,2,3,4 110532 0 0 ITEOS THERAPEUTICS INC COM 46565G104 25497 994047 SH DFND 1,2,3,4,5,6 994047 0 0 KALEIDO BIOSCIENCES INC COM 483347100 3724 500500 SH DFND 1,2,3,4,5,6 500500 0 0 KINNATE BIOPHARMA INC COM 49705R105 2910 125000 SH DFND 1,2,3,4,5,6 125000 0 0 KRONOS BIO INC COM 50107A104 31565 1317954 SH DFND 1,2,3,4,5,6 1317954 0 0 KRYSTAL BIOTECH INC COM 501147102 34000 500000 SH DFND 1,2,3,4,5,6 500000 0 0 KURA ONCOLOGY INC COM 50127T109 12510 600000 SH DFND 1,2,3,4,5,6 600000 0 0 KYMERA THERAPEUTICS INC COM 501575104 12125 250000 SH DFND 1,2,3,4,5,6 250000 0 0 LAVA THERAPEUTICS NV SHS N51517105 2176 200000 SH DFND 1,2,3,4,5,6 200000 0 0 LEAP THERAPEUTICS INC COM 52187K101 4920 3000000 SH DFND 1,2,3,4,5,6 3000000 0 0 LEXICON PHARMACEUTICALS INC COM NEW 528872302 16139 3516214 SH DFND 1,2,3,4,5,6 3516214 0 0 LEXICON PHARMACEUTICALS INC COM NEW 528872302 310569 67662150 SH DFND 1,2,3,4 67662150 0 0 LIFESTANCE HEALTH GROUP INC COM 53228F101 13930 500000 SH DFND 1,2,3,4,5,6 500000 0 0 LUFAX HOLDING LTD ADS REP SHS CL A 54975P102 565 50000 SH DFND 1,2,3,4,5,6 50000 0 0 LYELL IMMUNOPHARMA INC COM 55083R104 11368 700000 SH DFND 1,2,3,4,5,6 700000 0 0 MARINUS PHARMACEUTICALS INC COM NEW 56854Q200 17940 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 MEI PHARMA INC COM NEW 55279B202 2850 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 MEREO BIOPHARMA GROUP PLC ADS 589492107 4755 1500000 SH DFND 1,2,3,4,5,6 1500000 0 0 MERSANA THERAPEUTICS INC COM 59045L106 16296 1200000 SH DFND 1,2,3,4,5,6 1200000 0 0 METACRINE INC COM 59101E103 3515 924898 SH DFND 1,2,3,4,5,6 924898 0 0 MIRATI THERAPEUTICS INC COM 60468T105 137301 850000 SH DFND 1,2,3,4,5,6 850000 0 0 MOLECULAR PARTNERS AG ADS 60853G106 2049 100000 SH DFND 1,2,3,4,5,6 100000 0 0 MORPHIC HLDG INC COM 61775R105 104403 1819186 SH DFND 1,2,3,4,5,6 1819186 0 0 NANOBIOTIX SA SPONSORED ADS 63009J107 13780 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 NEXIMMUNE INC COM 65344D109 19584 1200000 SH DFND 1,2,3,4,5,6 1200000 0 0 NOVAGOLD RES INC COM NEW 66987E206 20826 2600000 SH DFND 1,2,3,4,5,6 2600000 0 0 OATLY GROUP AB SPONSORED ADS 67421J108 36690 1500000 SH DFND 1,2,3,4,5,6 1500000 0 0 OLEMA PHARMACEUTICALS INC COM 68062P106 7289 260500 SH DFND 1,2,3,4,5,6 260500 0 0 OMEGA ALPHA SPAC CL A G6749V107 7463 750000 SH DFND 1,2,3,4,5,6 750000 0 0 ORCHARD THERAPEUTICS PLC ADS 68570P101 7919 1803858 SH DFND 1,2,3,4,5,6 1803858 0 0 ORIC PHARMACEUTICALS INC COM 68622P109 7076 400000 SH DFND 1,2,3,4,5,6 400000 0 0 OVID THERAPEUTICS INC COM 690469101 9775 2500000 SH DFND 1,2,3,4,5,6 2500000 0 0 PRAXIS PRECISION MEDICINES I COM 74006W108 21936 1200000 SH DFND 1,2,3,4,5,6 1200000 0 0 RECURSION PHARMACEUTICALS IN CL A 75629V104 7300 200000 SH DFND 1,2,3,4,5,6 200000 0 0 RELAY THERAPEUTICS INC COM 75943R102 14636 400000 SH DFND 1,2,3,4,5,6 400000 0 0 REPARE THERAPEUTICS INC COM 760273102 17149 550000 SH DFND 1,2,3,4,5,6 550000 0 0 REPLIMUNE GROUP INC COM 76029N106 34578 900000 SH DFND 1,2,3,4,5,6 900000 0 0 RIGEL PHARMACEUTICALS INC COM NEW 766559603 1394 321100 SH DFND 1,2,3,4,5,6 321100 0 0 RUBIUS THERAPEUTICS INC COM 78116T103 113111 4633791 SH DFND 1,2,3,4,5,6 4633791 0 0 SAGE THERAPEUTICS INC COM 78667J108 56810 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 SANA BIOTECHNOLOGY INC COM 799566104 7864 400000 SH DFND 1,2,3,4,5,6 400000 0 0 SCHOLAR ROCK HLDG CORP COM 80706P103 57800 2000000 SH DFND 1,2,3,4,5,6 2000000 0 0 SCHRODINGER INC COM 80810D103 60295 797445 SH DFND 1,2,3,4,5,6 797445 0 0 SEER INC COM CL A 81578P106 183187 5588366 SH DFND 1,2,3,4,5,6 5588366 0 0 SELECTA BIOSCIENCES INC COM 816212104 16720 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SH DFND 1,2,3,4,5,6 750000 0 0 TG THERAPEUTICS INC COM 88322Q108 31032 800000 SH DFND 1,2,3,4,5,6 800000 0 0 TRANSLATE BIO INC COM 89374L104 13770 500000 SH DFND 1,2,3,4,5,6 500000 0 0 TRILLIUM THERAPEUTICS INC COM NEW 89620X506 24250 2500000 SH DFND 1,2,3,4,5,6 2500000 0 0 TURNING POINT THERAPEUTICS I COM 90041T108 27307 350000 SH DFND 1,2,3,4,5,6 350000 0 0 VERVE THERAPEUTICS INC COM 92539P101 30125 500000 SH DFND 1,2,3,4,5,6 500000 0 0 VIACOMCBS INC CL B 92556H206 3390 75000 SH DFND 1,2,3,4,5,6 75000 0 0 VOR BIOPHARMA INC COM 929033108 10258 550000 SH DFND 1,2,3,4,5,6 550000 0 0 WW INTL INC COM 98262P101 535533 14818300 SH DFND 1,2,3,4,7 14818300 0 0 Y-MABS THERAPEUTICS INC COM 984241109 13520 400000 SH DFND 1,2,3,4,5,6 400000 0 0 YUMANITY THERAPEUTICS INC COM 98872L102 2533 217391 SH DFND 1,2,3,4,5,6 217391 0 0 ZYMEWORKS INC COM 98985W102 15611 450000 SH DFND 1,2,3,4,5,6 450000 0 0