Authorized Person

0001053906-21-000005.txt : 20210514 0001053906-21-000005.hdr.sgml : 20210514 20210514152101 ACCESSION NUMBER: 0001053906-21-000005 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20210331 FILED AS OF DATE: 20210514 DATE AS OF CHANGE: 20210514 EFFECTIVENESS DATE: 20210514 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Artal Group S.A. CENTRAL INDEX KEY: 0001053906 IRS NUMBER: 000000000 STATE OF INCORPORATION: N4 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-15027 FILM NUMBER: 21924117 BUSINESS ADDRESS: STREET 1: VALLEY PARK STREET 2: 44, RUE DE LA VALLEE CITY: LUXEMBOURG STATE: N4 ZIP: L-2661 BUSINESS PHONE: (352) 22.42.59-1 MAIL ADDRESS: STREET 1: VALLEY PARK STREET 2: 44, RUE DE LA VALLEE CITY: LUXEMBOURG STATE: N4 ZIP: L-2661 FORMER COMPANY: FORMER CONFORMED NAME: ARTAL GROUP S A DATE OF NAME CHANGE: 19980128 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001053906 XXXXXXXX 03-31-2021 03-31-2021 false Artal Group S.A.

VALLEY PARK 44, RUE DE LA VALLEE LUXEMBOURG N4 L-2661

13F HOLDINGS REPORT 028-15027 Y The Reporting Manager does not have formal investment discretion with respect to all of the securities in the indicated rows in the Form 13F Information Table, but may be deemed to be part of a group exercising such investment discretion. Such group, if any, would include the managers identified in the column captioned "Other Managers" relating to a given issuer. The filing of this report shall not be deemed an admission, for purposes of Section 13(f), 13(d), 13(g), or 16(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the rules thereunder, or for any other purpose, that the Reporting Manager or any Other Manager exercises investment discretion or is a member of such a group with respect to such securities. Reference is made to reports filed under Sections 13(d), 13(g), and 16(a) for additional information with respect to such beneficial ownership and/or pecuniary interest of the Reporting Manager, any Other Manager and related entities. Anne Goffard Authorized Person 352224259-1 /s/ Anne Goffard Luxembourg N4 05-14-2021 7 148 5659662 1 0001460840 028-15028 Stichting Administratiekantoor Westend 2 0001283968 028-15029 Westend S.A. 3 0001522131 028-15031 Artal International Management S.A. 4 0001218180 028-15033 Artal International S.C.A. 5 0001766952 028-19088 Artal Treasury Ltd 6 0001340096 028-11522 Invus Public Equities Advisors, LLC 7 0001053905 028-19506 Artal Luxembourg S. A. INFORMATION TABLE 2 infotable.xml 111 INC ADS 68247Q102 13336 966349 SH DFND 1,2,3,4,5,6 966349 0 0 AC IMMUNE SA SHS H00263105 7610 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 ACCELERON PHARMA INC COM 00434H108 189854 1400000 SH DFND 1,2,3,4,5,6 1400000 0 0 ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 37326 2255375 SH DFND 1,2,3,4,5,6 2255375 0 0 ADAGENE INC ADS 005329107 14360 800000 SH DFND 1,2,3,4,5,6 800000 0 0 ADVERUM BIOTECHNOLOGIES INC COM 00773U108 23664 2400000 SH DFND 1,2,3,4,5,6 2400000 0 0 AEGLEA BIOTHERAPEUTICS INC COM 00773J103 8276 1045000 SH DFND 1,2,3,4,5,6 1045000 0 0 AGENUS INC COM NEW 00847G705 16320 6000000 SH DFND 1,2,3,4,5,6 6000000 0 0 ALBIREO PHARMA INC COM 01345P106 21150 600000 SH DFND 1,2,3,4,5,6 600000 0 0 ALCOA CORP COM 013872106 48735 1500000 SH Call DFND 1,2,3,4,5,6 1500000 0 0 ALLOVIR INC COM 019818103 54367 2323371 SH DFND 1,2,3,4,5,6 2323371 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 105893 750000 SH DFND 1,2,3,4,5,6 750000 0 0 ALPINE IMMUNE SCIENCES INC COM 02083G100 6286 593030 SH DFND 1,2,3,4,5,6 593030 0 0 ALX ONCOLOGY HLDGS INC COM 00166B105 38714 525000 SH DFND 1,2,3,4,5,6 525000 0 0 AMICUS THERAPEUTICS INC COM 03152W109 37050 3750000 SH DFND 1,2,3,4,5,6 3750000 0 0 APPLIED THERAPEUTICS INC COM 03828A101 7502 400000 SH DFND 1,2,3,4,5,6 400000 0 0 APTINYX INC COM 03836N103 18349 6116493 SH DFND 1,2,3,4,5,6 6116493 0 0 ARAVIVE INC COM 03890D108 8641 1311291 SH DFND 1,2,3,4,5,6 1311291 0 0 ARGENX SE SPONSORED ADR 04016X101 123926 450000 SH DFND 1,2,3,4,5,6 450000 0 0 ATARA BIOTHERAPEUTICS INC COM 046513107 28720 2000000 SH DFND 1,2,3,4,5,6 2000000 0 0 AURINIA PHARMACEUTICALS INC COM 05156V102 12985 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 AVIDITY BIOSCIENCES INC COM 05370A108 3108 142500 SH DFND 1,2,3,4,5,6 142500 0 0 AVIS BUDGET GROUP COM 053774105 32643 450000 SH DFND 1,2,3,4,5,6 450000 0 0 AXCELLA HEALTH INC COM 05454B105 3392 712500 SH DFND 1,2,3,4,5,6 712500 0 0 BK OF AMERICA CORP COM 060505104 77380 2000000 SH Call DFND 1,2,3,4,5,6 2000000 0 0 BEIGENE LTD SPONSORED ADR 07725L102 295868 850000 SH DFND 1,2,3,4,5,6 850000 0 0 BELLUS HEALTH INC NEW COM NEW 07987C204 18240 4750000 SH DFND 1,2,3,4,5,6 4750000 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 11327 150000 SH Call DFND 1,2,3,4,5,6 150000 0 0 BIONTECH SE SPONSORED ADS 09075V102 98271 900000 SH DFND 1,2,3,4 900000 0 0 BLACK DIAMOND THERAPEUTICS I COM 09203E105 39945 1646517 SH DFND 1,2,3,4,5,6 1646517 0 0 BRIDGEBIO PHARMA INC COM 10806X102 15400 250000 SH DFND 1,2,3,4,5,6 250000 0 0 BRISTOL-MYERS SQUIBB CO COM 110122108 63130 1000000 SH Call DFND 1,2,3,4,5,6 1000000 0 0 BROADCOM INC COM 11135F101 34775 75000 SH DFND 1,2,3,4,5,6 75000 0 0 CARDIFF ONCOLOGY INC COM 14147L108 6945 750000 SH DFND 1,2,3,4,5,6 750000 0 0 CEREVEL THERAPEUTICS HLDNG I *W EXP 06/09/202 15678U102 343 79600 SH DFND 1,2,3,4,5,6 79600 0 0 CEREVEL THERAPEUTICS HLDNG I COM 15678U128 34325 2500000 SH DFND 1,2,3,4,5,6 2500000 0 0 CHEMOCENTRYX INC COM 16383L106 38430 750000 SH DFND 1,2,3,4,5,6 750000 0 0 CHIASMA INC COM 16706W102 1189 380000 SH DFND 1,2,3,4,5,6 380000 0 0 CHINOOK THERAPEUTICS INC COM 16961L106 2805 180500 SH DFND 1,2,3,4,5,6 180500 0 0 CIDARA THERAPEUTICS INC COM 171757107 598 224675 SH DFND 1,2,3,4,5,6 224675 0 0 CITIGROUP INC COM NEW 172967424 218250 3000000 SH Call DFND 1,2,3,4,5,6 3000000 0 0 CODIAK BIOSCIENCES INC COM 192010106 3016 200000 SH DFND 1,2,3,4,5,6 200000 0 0 CONTRAFECT CORP COM NEW 212326300 7200 1500000 SH DFND 1,2,3,4,5,6 1500000 0 0 COUPANG INC CL A 22266T109 19740 400000 SH DFND 1,2,3,4,5,6 400000 0 0 CULLINAN ONCOLOGY INC COM 230031106 4167 100000 SH DFND 1,2,3,4,5,6 100000 0 0 CURIS INC COM NEW 231269200 20430 1804729 SH DFND 1,2,3,4,5,6 1804729 0 0 CYCLERION THERAPEUTICS INC COM 23255M105 5040 1806531 SH DFND 1,2,3,4,5,6 1806531 0 0 CYCLERION THERAPEUTICS INC COM 23255M105 31 11053 SH DFND 1,2,3,4 11053 0 0 DECIPHERA PHARMACEUTICALS IN COM 24344T101 8968 200000 SH DFND 1,2,3,4,5,6 200000 0 0 DENALI THERAPEUTICS INC COM 24823R105 28550 500000 SH DFND 1,2,3,4,5,6 500000 0 0 DESIGN THERAPEUTICS INC COM 25056L103 11960 400000 SH DFND 1,2,3,4,5,6 400000 0 0 DICERNA PHARMACEUTICALS INC COM 253031108 20456 800000 SH DFND 1,2,3,4,5,6 800000 0 0 DYNE THERAPEUTICS INC COM 26818M108 8153 525000 SH DFND 1,2,3,4,5,6 525000 0 0 EVELO BIOSCIENCES INC COM 299734103 10700 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 FATE THERAPEUTICS INC COM 31189P102 107185 1300000 SH DFND 1,2,3,4,5,6 1300000 0 0 FOGHORN THERAPEUTICS INC COM 344174107 22679 1720720 SH DFND 1,2,3,4,5,6 1720720 0 0 FORD MTR CO DEL COM 345370860 85750 7000000 SH Call DFND 1,2,3,4,5,6 7000000 0 0 FORMA THERAPEUTICS HLDGS INC SHS 34633R104 28020 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 FREEPORT-MCMORAN INC CL B 35671D857 32930 1000000 SH Call DFND 1,2,3,4,5,6 1000000 0 0 FUSION PHARMACEUTICALS INC COM 36118A100 5781 539264 SH DFND 1,2,3,4,5,6 539264 0 0 GDS HLDGS LTD SPONSORED ADS 36165L108 8109 100000 SH DFND 1,2,3,4,5,6 100000 0 0 GENERAL MTRS CO COM 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INC COM 45826J105 20064 250000 SH DFND 1,2,3,4,5,6 250000 0 0 IOVANCE BIOTHERAPEUTICS INC COM 462260100 12664 400000 SH DFND 1,2,3,4,5,6 400000 0 0 IQIYI INC SPONSORED ADS 46267X108 17036 1025000 SH DFND 1,2,3,4,5,6 1025000 0 0 IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 1236 110532 SH DFND 1,2,3,4 110532 0 0 ITEOS THERAPEUTICS INC COM 46565G104 37395 1094047 SH DFND 1,2,3,4,5,6 1094047 0 0 KALEIDO BIOSCIENCES INC COM 483347100 4054 500500 SH DFND 1,2,3,4,5,6 500500 0 0 KE HLDGS INC SPONSORED ADS 482497104 34188 600000 SH DFND 1,2,3,4,5,6 600000 0 0 KINNATE BIOPHARMA INC COM 49705R105 3895 125000 SH DFND 1,2,3,4,5,6 125000 0 0 KRANESHARES TR CSI CHI INTERNET 500767306 15270 200000 SH Call DFND 1,2,3,4,5,6 200000 0 0 KRONOS BIO INC COM 50107A104 38577 1317954 SH DFND 1,2,3,4,5,6 1317954 0 0 KRYSTAL BIOTECH INC COM 501147102 38520 500000 SH DFND 1,2,3,4,5,6 500000 0 0 KURA ONCOLOGY INC COM 50127T109 16962 600000 SH DFND 1,2,3,4,5,6 600000 0 0 KYMERA THERAPEUTICS INC COM 501575104 9715 250000 SH DFND 1,2,3,4,5,6 250000 0 0 LAVA THERAPEUTICS NV SHS N51517105 3038 200000 SH DFND 1,2,3,4,5,6 200000 0 0 LEAP THERAPEUTICS INC COM 52187K101 5700 3000000 SH DFND 1,2,3,4,5,6 3000000 0 0 LEXICON PHARMACEUTICALS INC COM NEW 528872302 20640 3516214 SH DFND 1,2,3,4,5,6 3516214 0 0 LEXICON PHARMACEUTICALS INC COM NEW 528872302 397177 67662150 SH DFND 1,2,3,4 67662150 0 0 MANCHESTER UTD PLC NEW ORD CL A G5784H106 197 12488 SH DFND 1,2,3,4,5,6 12488 0 0 MARINUS PHARMACEUTICALS INC COM NEW 56854Q200 12384 800000 SH DFND 1,2,3,4,5,6 800000 0 0 MEI PHARMA INC COM NEW 55279B202 2607 760000 SH DFND 1,2,3,4,5,6 760000 0 0 MEREO BIOPHARMA GROUP PLC ADS 589492107 5055 1500000 SH DFND 1,2,3,4,5,6 1500000 0 0 MERSANA THERAPEUTICS INC COM 59045L106 19416 1200000 SH DFND 1,2,3,4,5,6 1200000 0 0 METACRINE INC COM 59101E103 5734 924898 SH DFND 1,2,3,4,5,6 924898 0 0 MIRATI THERAPEUTICS INC COM 60468T105 124193 725000 SH DFND 1,2,3,4,5,6 725000 0 0 MORPHIC HLDG INC COM 61775R105 115118 1819186 SH DFND 1,2,3,4,5,6 1819186 0 0 NANOBIOTIX SA SPONSORED ADS 63009J107 15040 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 NEXIMMUNE INC COM 65344D109 22896 1200000 SH DFND 1,2,3,4,5,6 1200000 0 0 NOVAGOLD RES INC COM NEW 66987E206 22776 2600000 SH DFND 1,2,3,4,5,6 2600000 0 0 OLEMA PHARMACEUTICALS INC COM 68062P106 8643 260500 SH DFND 1,2,3,4,5,6 260500 0 0 OMEGA ALPHA SPAC CL A G6749V107 7425 750000 SH DFND 1,2,3,4,5,6 750000 0 0 ORCHARD THERAPEUTICS PLC ADS 68570P101 13096 1803858 SH DFND 1,2,3,4,5,6 1803858 0 0 ORIC PHARMACEUTICALS INC COM 68622P109 2450 100000 SH DFND 1,2,3,4,5,6 100000 0 0 OVID THERAPEUTICS INC COM 690469101 10050 2500000 SH DFND 1,2,3,4,5,6 2500000 0 0 PRAXIS PRECISION MEDICINES I COM 74006W108 24570 750000 SH DFND 1,2,3,4,5,6 750000 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 1943 75000 SH DFND 1,2,3,4,5,6 75000 0 0 RELAY THERAPEUTICS INC COM 75943R102 13828 400000 SH DFND 1,2,3,4,5,6 400000 0 0 REPARE THERAPEUTICS INC COM 760273102 16880 550000 SH DFND 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TENCENT MUSIC ENTMT GROUP SPONSORED ADS 88034P109 11270 550000 SH DFND 1,2,3,4,5,6 550000 0 0 TG THERAPEUTICS INC COM 88322Q108 72300 1500000 SH DFND 1,2,3,4,5,6 1500000 0 0 TRANSLATE BIO INC COM 89374L104 16490 1000000 SH DFND 1,2,3,4,5,6 1000000 0 0 TRILLIUM THERAPEUTICS INC COM NEW 89620X506 26850 2500000 SH DFND 1,2,3,4,5,6 2500000 0 0 TRIP COM GROUP LTD ADS 89677Q107 9908 250000 SH DFND 1,2,3,4,5,6 250000 0 0 TURNING POINT THERAPEUTICS I COM 90041T108 29578 312700 SH DFND 1,2,3,4,5,6 312700 0 0 VIACOMCBS INC CL B 92556H206 3044 67500 SH DFND 1,2,3,4,5,6 67500 0 0 VOR BIOPHARMA INC COM 929033108 23705 550000 SH DFND 1,2,3,4,5,6 550000 0 0 WW INTL INC COM 98262P101 463516 14818300 SH DFND 1,2,3,4,7 14818300 0 0 Y-MABS THERAPEUTICS INC COM 984241109 12096 400000 SH DFND 1,2,3,4,5,6 400000 0 0 YUMANITY THERAPEUTICS INC COM 98872L102 3935 217391 SH DFND 1,2,3,4,5,6 217391 0 0 ZILLOW GROUP INC CL C CAP STK 98954M200 12964 100000 SH DFND 1,2,3,4,5,6 100000 0 0 ZYMEWORKS INC COM 98985W102 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