Note 13 - Income Taxes - Deferred Tax Assets and Liabilities (Details) - USD ($)	Dec. 31, 2024	Dec. 31, 2023
Net operating loss	$ 10,417,666	$ 10,495,881
Research and development credits	1,228,255	708,443
Capitalized research expenditures	6,392,545	2,271,853
Stock-based compensation	698,886	567,473
Charitable contributions	1,321	0
Intangibles	193,106	223,548
Gross deferred tax assets	18,931,779	14,267,198
Less valuation allowance	(18,557,844)	(14,100,543)
Total deferred tax assets	373,935	166,655
Prepaids	(373,935)	(166,655)
Gross deferred tax liabilities	(373,935)	(166,655)
Deferred tax assets, net	$ 0	$ 0