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Note 13 - Income Taxes - Rate Reconciliation of Income Tax Rate (Details)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Federal tax benefit at statutory rate 21.00% 21.00%
State tax, net of federal benefit 4.40% 6.30%
Change in convertible debt 0.00% 52.80%
Research and development credits 3.20% 17.10%
Change in valuation allowance (27.30%) (95.90%)
Share-based compensation (1.10%) (1.00%)
Other (0.20%) (0.30%)
Total provision 0.00% 0.00%