Note 6 - Significant Agreements and Contracts (Details Textual) - USD ($)	1 Months Ended		12 Months Ended
	Mar. 31, 2025	Aug. 31, 2014	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023	Aug. 31, 2024	Jan. 31, 2023
Research and Development Expense				$ 18,798,343	$ 8,438,499
Government Assistance, Asset				21,300,000
Revenues				9,737,974	7,144,872
Vertex Option and License Agreement [Member]
Research and Development Expense		$ 100,000
Contractual Obligation		117,000,000
Payments for License Agreement		$ 100,000		0	0
National Institute of Aging Grant [Member]
Government Assistance, Asset						$ 300,000	$ 21,000,000
Government Assistance, Income, Increase (Decrease)	$ 5,600,000			8,300,000	6,700,000
Revenues				9,700,000	$ 7,100,000
Proceeds From Grants				14,600,000
Grant Funding Remaining				6,600,000
Deferred Revenue, Current				$ 2,300,000
Grant Amount, Received, Parentage	90.00%
National Institute of Aging Grant [Member] | Forecast [Member]
Government Assistance, Income, Increase (Decrease)			$ 6,200,000