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Note 4 - Significant Agreements and Contracts (10-Q) (Details Textual)
$ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Feb. 29, 2024
USN ($)
Aug. 31, 2014
USD ($)
Jun. 30, 2024
Mar. 31, 2024
USD ($)
Mar. 31, 2023
USD ($)
Dec. 31, 2025
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Jan. 31, 2023
USD ($)
Jan. 01, 2023
USN ($)
Research and Development Expense       $ 2,814,258 $ 1,833,274     $ 8,438,499 $ 1,336,469    
Revenues       2,347,250 1,407,868     7,144,872 0    
Vertex Option and License Agreement [Member]                      
Research and Development Expense   $ 100,000                  
Contractual Obligation   117,000,000   117,000,000              
Payments for License Agreement   $ 100,000           0 $ 0    
National Institute of Aging Grant [Member]                      
Government Assistance, Asset                   $ 21,000,000 $ 21.0
Government Assistance, Income, Increase (Decrease) $ 7.3     6,700,000       6,700,000      
Revenues       2,300,000 $ 1,400,000     7,100,000      
Proceeds From Grants       10,100,000       6,200,000      
Grant Funding Remaining       $ 10,900,000       $ 15,800,000      
Grant Amount, Received, Parentage 90.00%                    
National Institute of Aging Grant [Member] | Forecast [Member]                      
Government Assistance, Income, Increase (Decrease)           $ 6,200,000 $ 8,100,000        
Grant Amount, Received, Parentage     10.00%