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Note 7 - Stockholders' Equity and Common Stock Warrants (Details Textual)	3 Months Ended
	Mar. 31, 2023 shares
Class of Warrant or Rights, Expired	23,639

X

- Definition

Number of warrants or rights expired.

+ References

No definition available.

+ Details

Name:	dffn_ClassOfWarrantOrRightsExpired
Namespace Prefix:	dffn_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	duration