Consolidated Statements of Changes in Stockholders' Equity - USD ($)	Common Stock [Member]	Additional Paid-in Capital [Member]	Retained Earnings [Member]	Total
Balance (in shares) at Dec. 31, 2019	33,480,365
Balance at Dec. 31, 2019	$ 33,481	$ 111,824,859	$ (91,724,078)	$ 20,134,262
Issuance of common stock, pre-funded warrants and warrants, net of issuance costs (in shares)	11,428,572
Issuance of common stock, pre-funded warrants and warrants, net of issuance costs	$ 11,429	10,330,202	0	10,341,631
Issuance of common stock upon exercise of warrants (in shares)	19,106,504
Issuance of common stock upon exercise of warrants	$ 19,106	7,768,370	0	7,787,476
Stock-based compensation expense	0	736,119	0	736,119
Net loss	$ 0	0	(14,185,306)	(14,185,306)
Balance (in shares) at Dec. 31, 2020	64,015,441
Balance at Dec. 31, 2020	$ 64,016	130,659,550	(105,909,384)	24,814,182
Issuance of common stock, pre-funded warrants and warrants, net of issuance costs (in shares)	33,658,538
Issuance of common stock, pre-funded warrants and warrants, net of issuance costs	$ 33,658	31,060,644	0	31,094,302
Issuance of common stock upon exercise of warrants (in shares)	4,230,000
Issuance of common stock upon exercise of warrants	$ 4,230	2,197,220	0	2,201,450
Stock-based compensation expense	0	897,260	0	897,260
Net loss	$ 0	0	(24,095,727)	(24,095,727)
Vesting of restricted stock units (in shares)	10,301
Vesting of restricted stock units	$ 10	(10)	0	0
Balance (in shares) at Dec. 31, 2021	101,914,280
Balance at Dec. 31, 2021	$ 101,914	$ 164,814,664	$ (130,005,111)	$ 34,911,467