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Note 3 - Basis of Presentation and Summary of Significant Accounting Policies (Tables)
3 Months Ended
Mar. 31, 2019
Notes Tables  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   
March 31,
 
   
2019
   
2018
 
Convertible debt
   
     
14,325
 
Common stock warrants
   
2,087,012
     
2,113,815
 
Stock options
   
256,057
     
203,586
 
Unvested restricted stock awards
   
     
102
 
     
2,343,069
     
2,331,828