Note 8 - Accrued Expenses and Other Current Liabilities - Summary of Accrued Expenses (Details) - USD ($)	Dec. 31, 2016	Dec. 31, 2015
Accrued interest payable	$ 29,359	$ 14,009
Accrued payroll and payroll related expenses	399,740	56,947
Accrued professional fees	72,855	327,950
Accrued clinical studies expenses	220,978	184,737
Other	151,332	38,026
Total	$ 874,264	$ 621,669