Note 4 - Acquisitions (Tables)

12 Months Ended

Dec. 31, 2016

Notes Tables

Business Combination, Preliminary Purchase Price Consideration [Table Text Block]

Fair value of the Company’s pre-Merger shares outstanding	$	19,546,000
Estimated fair value of the Company’s pre-Merger stock options outstanding		1,321,000
Estimated fair value of the Company’s pre-Merger warrants outstanding		384,000
CVRs – RES-440 product candidate		10,000
Total purchase price	$	21,261,000

Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block]

Cash and cash equivalents	$	8,500,602
Prepaid expenses and other assets		195,200
Property and equipment		57,531
Intangible assets		9,600,000
Goodwill		6,929,258
Accrued liabilities		(377,432	)
Deferred tax liability		(3,644,159	)
Net assets acquired	$	21,261,000

Business Acquisition, Pro Forma Information [Table Text Block]

	Year ended December 3 1 ,
	2016			2015
Net revenues	$	—		$	—
Net loss	$	(16,471,398	)	$	(17,618,292	)
Basic and diluted loss per share	$	(1.60	)	$	(3.89	)