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Note 2 - Basis of Presentation and Significant Accounting Policies (Details Textual) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
General and Administrative Expense [Member]        
Prior Period Reclassification Adjustment, Stock-Based Compensation and Warrant Expense   $ 440,935   $ 699,310
Research and Development Expense [Member]        
Prior Period Reclassification Adjustment, Stock-Based Compensation and Warrant Expense   342,997   375,821
Accounts Payable and Accrued Liabilities [Member]        
Prior Period Reclassification Adjustment, Loss on Settlement of Issuing Shares for Liabilities       482,373
Income Tax Expense (Benefit) $ (145,999) $ 0 (384,128)
Gains (Losses) on Extinguishment of Related Party Debt (1,829,562)
Gain (Loss) on Settlement of Notes Payable (876,543)
Prior Period Reclassification Adjustment Income Tax Benefit   $ 145,999   384,128
Prior Period Reclassification Adjustment, Amortization of Prepaid Expense Asset   286,774   860,322
Prior Period Reclassification Adjustment, Stock-Based Compensation and Warrant Expense   783,932   1,075,131
Prior Period Reclassification Adjustment, Employee and Director Stock-Based Compensation NonCash       1,075,131
Prior Period Reclassification Adjustment, Legal and Professional Services   $ 294,390   810,680
Prior Period Reclassification Adjustment, Loss on Settlement of Issuing Shares for Liabilities       408,953
Prior Period Reclassification Adjustment, Notes Payable Settlements       $ 73,420