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Income Taxes (Details 1) (USD $) In Thousands, unless otherwise specified	Dec. 31, 2012	Dec. 31, 2011
Deferred tax assets:
Net operating loss carryforwards	$ 26,471	$ 20,256
Capitalized research and developmental costs	26,511	24,023
Non-cash compensation	3,200	2,834
Total deferred tax assets	56,182	47,113
Less valuation allowance	(56,182)	(47,113)
Net deferred tax assets

Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from in-process research and development costs expensed in connection with a business combination.

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- Definition

Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards.

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- Definition

Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from other compensation and benefits not separately disclosed.

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- Definition

Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized.

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