Related Parties (Details) $ / shares in Units, $ in Thousands						1 Months Ended	2 Months Ended	12 Months Ended
	May 29, 2018 USD ($) $ / shares shares	Mar. 30, 2018 USD ($) $ / shares shares	Sep. 20, 2017 USD ($) shares	Jun. 22, 2015 USD ($) shares $ / shares	Jul. 21, 2014 USD ($) shares $ / shares	Jul. 31, 2018 shares	May 29, 2018 USD ($) $ / shares	Dec. 31, 2018 USD ($) shares $ / shares	Dec. 31, 2017 USD ($) Director shares
Related Party Transaction [Abstract]
Sale of common stock, net of offering costs							$ 17,000	$ 14,664
Sale of common stock, net of offering costs (in shares) | shares						153,004
Debentures converted into shares of common stock, value								0	$ 262
Series C Convertible Preferred Stock [Member]
Related Party Transaction [Abstract]
Debentures converted into shares of common stock, value			$ 40,465
Debt conversion, converted instrument, issued (in shares) | shares			40,482
Senior Secured 2.25% Convertible Debentures [Member]
Related Party Transaction [Abstract]
Aggregate principal amount of debt								$ 32,500
Number of shares debt convertible (in shares) | shares								8,666,668
Debt instrument conversion price (in dollars per share) | $ / shares								$ 3.75
Interest rate								2.25%
Maturity period								5 years
Senior Secured 4% Convertible Debentures [Member]
Related Party Transaction [Abstract]
Aggregate principal amount of debt					$ 15,000			$ 15,000
Number of shares debt convertible (in shares) | shares					1,169,595
Debt instrument conversion price (in dollars per share) | $ / shares					$ 12.825
Interest rate					4.00%
Maturity period								5 years
Debentures converted into shares of common stock, value									$ 262
Debt conversion, converted instrument, issued (in shares) | shares									70,000
Sabby Management LLC and Broadfin LLC [Member]
Related Party Transaction [Abstract]
Number of shares underlying warrants (in shares) | shares				600,000
Exercise price of warrants (in dollars per share) | $ / shares				$ 3.75
Sabby Management LLC and Broadfin LLC [Member] | Senior Secured 2.25% Convertible Debentures [Member]
Related Party Transaction [Abstract]
Exercise price of warrants (in dollars per share) | $ / shares				$ 3.75
Aggregate principal amount of debt				$ 32,500
Number of shares debt convertible (in shares) | shares				8,666,668
Debt instrument conversion price (in dollars per share) | $ / shares				$ 3.75
Interest rate				2.25%
Maturity period								5 years
Two Board Directors [Member]
Related Party Transaction [Abstract]
Number of directors | Director									2
Monthly retainer fee									$ 10
Related parties general and administrative expenses									180
Son of Former Board Member [Member]
Related Party Transaction [Abstract]
Related party expenses								$ 13	$ 30
Broadfin Capital and Sabby Management Stock Purchase Agreements [Member] | Sabby Management LLC and Broadfin LLC [Member]
Related Party Transaction [Abstract]
Sale of common stock, net of offering costs		$ 1,000
Sale of common stock, net of offering costs (in shares) | shares		925,926
Share price (in dollars per share) | $ / shares		$ 1.08
Broadfin Capital and Sabby Management Stock Purchase Agreements [Member] | Broadfin Capital [Member]
Related Party Transaction [Abstract]
Sale of common stock, net of offering costs		$ 1,000
Sale of common stock, net of offering costs (in shares) | shares		925,926
Share price (in dollars per share) | $ / shares		$ 1.08
Subscription Agreement [Member] | Dr. Dolev Rafaeli [Member]
Related Party Transaction [Abstract]
Sale of common stock, net of offering costs	$ 1,000
Sale of common stock, net of offering costs (in shares) | shares	925,926
Share price (in dollars per share) | $ / shares	$ 1.08						$ 1.08