Related Parties (Details) $ / shares in Units, $ in Thousands		12 Months Ended
	Nov. 04, 2015 USD ($)	Dec. 31, 2016 USD ($) shares $ / shares
Senior Secured 2.25% Convertible Debentures [Member]
Related Party Transaction [Line Items]
Aggregate principal amount of debt		$ 32,500
Interest rate		2.25%
Number of shares debt convertible (in shares) | shares		43,333,334
Initial conversion price (in dollars per share) | $ / shares		$ 0.75
Maturity period		5 years
Maturity date		Jun. 30, 2021
Sabby Management LLC and Broadfin LLC [Member] | Senior Secured 2.25% Convertible Debentures [Member]
Related Party Transaction [Line Items]
Aggregate principal amount of debt		$ 32,500
Interest rate		2.25%
Number of shares underlying warrants (in shares) | shares		3,000,000
Exercise price of warrants (in dollars per share) | $ / shares		$ 0.75
Number of shares debt convertible (in shares) | shares		43,333,334
Initial conversion price (in dollars per share) | $ / shares		$ 0.75
Maturity period		5 years
Maturity date		Jun. 30, 2021
Percentage of liquidated damages payable		2.00%
Percentage of aggregate liquidated damages payable		12.00%
Interest rate payable on liquidated damages		12.00%
Percentage of issued and outstanding common stock payable upon conversion		9.99%
Sabby Management LLC and Broadfin LLC [Member] | Senior Secured Notes Payable [Member]
Related Party Transaction [Line Items]
Aggregate principal amount of debt		$ 10,000
Number of days for stockholders approval considered for maturity date		30 days
Interest rate		9.00%
Two Board Directors [Member]
Related Party Transaction [Line Items]
Up-front fee paid	$ 40,000
Monthly retainer fee		$ 10,000